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Chapter and Conference Paper
Automated Design of Assemblable, Modular, Synthetic Chromosomes
The goal of the Saccharomyces cerevisiae v2.0 project is the complete synthesis of a re-designed genome for baker’s yeast. The resulting organism will permit systematic studies of eukaryotic chromosome structure ...
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Chapter and Conference Paper
Probabilistic Paths for Protein Complex Inference
Understanding how individual proteins are organized into complexes and pathways is a significant current challenge. We introduce new algorithms to infer protein complexes by combining seed proteins with a conf...