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    Inhibition of Sonic Hedgehog signaling reduces tumor growth in pancreatic cancer in vitro and in vivo

    Introduction: Activation of the hedgehog signal transduction pathway, triggered by hedgehog binding to the transmembrane receptor PTCH or by mutations in the PTCH gene, plays an important role in...

    Priv.-Doz. Dr. M. Bahra, U. P. Neumann, D. Jacob… in Chirurgisches Forum und DGAV Forum 2009 (2009)