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  2. Advanced Targeting Strategies for Murine Retroviral and Adeno-associated Viral Vectors

    Targeted gene delivery involves broadening viral tropism to infect previously nonpermissive cells, replacing viral tropism to infect a target cell...
    Julie H. Yu, David V. Schaffer in Gene Therapy and Gene Delivery Systems
    Chapter

  3. Nonviral Delivery of Cancer Genetic Vaccines

    The potential use of genetic vaccines to address numerous diseases including cancer is promising, but currently unrealized. Here, we review...
    Steven R. Little, Robert Langer in Gene Therapy and Gene Delivery Systems
    Chapter

  4. Production and Formulation of Adenovirus Vectors

    Adenovirus vectors have attracted considerable interest over the past decade, with ongoing clinical development programs for applications ranging...
    Nedim E. Altaras, John G. Aunins, ... Jayanthi J. Wolf in Gene Therapy and Gene Delivery Systems
    Chapter

  5. Molecular Conjugates

    Molecular conjugates are nanometer-sized entities consisting of synthetic materials (lipids, polycations, targeting agents, and so on) and nucleic...
    Jeremy Heidel, Swaroop Mishra, Mark E. Davis in Gene Therapy and Gene Delivery Systems
    Chapter

  6. Adeno-associated Virus as a Gene Therapy Vector: Vector Development, Production and Clinical Applications

    Adeno-associated virus (AAV) has emerged as an attractive vector for gene therapy. AAV vectors have successfully been utilized to promote...
    Joshua C. Grieger, Richard J. Samulski in Gene Therapy and Gene Delivery Systems
    Chapter

  7. Lentiviral Vectors

    We review the use of lentiviral vectors in current human gene therapy applications that involve genetic modification of nondividing tissues with...
    Nils Loewen, Eric M. Poeschla in Gene Therapy and Gene Delivery Systems
    Chapter

  8. Plasmid Vaccines and Therapeutics: From Design to Applications

    In the late 1980s, Vical and collaborators discovered that the injection into tissues of unformulated plasmid encoding various proteins resulted in...
    Marston Manthorpe, Peter Hobart, ... Alain Rolland in Gene Therapy and Gene Delivery Systems
    Chapter

  11. Obesity and Disease

    ...
    Alfred Poulos in Obesity in the 21st Century
    Chapter 2023

  13. Correction to: Learning Strategies in Protein Directed Evolution

    Xavier F. Cadet, Jean Christophe Gelly, ... Carlos G. Acevedo-Rocha in Directed Evolution
    Protocol 2023

  14. Drugs and Weight Loss

    ...
    Alfred Poulos in Obesity in the 21st Century
    Chapter 2023

  15. Surgery and Weight Loss

    ...
    Alfred Poulos in Obesity in the 21st Century
    Chapter 2023

  17. Diet and Obesity

    ...
    Alfred Poulos in Obesity in the 21st Century
    Chapter 2023

  19. Genetics and Obesity

    ...
    Alfred Poulos in Obesity in the 21st Century
    Chapter 2023

  20. Das menschliche Genom und seine Variationen

    In diesem Kapitel wird die genetische Anpassung des anatomisch modernen Menschen (Homo sapiens) durch Migration in neue geografische und klimatische...
    Carsten Carlberg, Lars-Oliver Klotz, Ferdinand Molnár in Nutrigenomik
    Chapter 2022
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