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Regeneration of Articular Cartilage
Loss of articular cartilage from the ends of bones forming diarthrodial joints can be the source of profound pain and disability, and eventually lead... -
Tissue Engineering Strategies for Bone Regeneration
Bone loss due to trauma or disease is an increasingly serious health problem. Current clinical treatments for critical-sized defects are problematic... -
Regeneration of Urologic Tissues and Organs
Patients suffering from a variety of urologic diseases may be treated with transplanted tissues and organs. However, there is a shortage of donor... -
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Heart Valve Regeneration
The valves of the heart cannot regenerate spontaneously. Therefore, heart valve disease generally necessitates surgical repair or replacement of the... -
Simultaneous In Vivo Regeneration of Neodermis, Epidermis, and Basement Membrane
Full-thickness skin loss does not undergo complete spontaneous regeneration in mammals. To restore the normal function of skin, dermal and epidermal... -
Effects of Sex Steroids on Innate and Adaptive Immunity
Estrogens and androgens are classically recognized as reproductive sex steroid hormones because of their well-documented effects on reproductive... -
Spinal Cord Regeneration
Repairing the damaged spinal cord has for a long time eluded neuroscientists. Few other achievements in neuroscience would have such a tremendous... -
Peripheral Nerve Regeneration
The nerve chamber model has dominated the experimental study of peripheral nerve (PN) regeneration with animal models as well as in several clinical... -
Post-traumatic Epilepsy and Neuropsychiatric Comorbidities
Post-traumatic epilepsy (PTE) is a form of acquired epilepsy that arises from traumatic brain injury (TBI). It presents a complex relationship with... -
Clostridioides difficile Biofilm
Clostridioides difficile infection (CDI), previously Clostridium difficile infection, is a symptomatic infection of the large intestine caused by the... -
Ribotypes and New Virulent Strains Across Europe
Clostridioides (formerly Clostridium) difficile is a major bacterial cause of post-antibiotic diarrhoea. The epidemiology of C. difficile infections... -
Diagnostic Guidance for C. difficile Infections
Diagnosis of Clostridioides difficile infection (CDI) can be challenging. First of all, there has been debate on which of the two reference assays,... -
Non-human Clostridioides difficile Reservoirs and Sources: Animals, Food, Environment
Clostridioides difficile is ubiquitous and is found in humans, animals and in variety of environments. The substantial overlap of ribotypes between... -
Immunization Strategies Against Clostridioides difficile
Clostridioides difficile (C. difficile) infection (CDI) is an important healthcare but also a community-associated disease. CDI is considered a... -
Probiotics for Prevention and Treatment of Clostridium difficile Infection
Probiotics have been claimed as a valuable tool to restore the balance in the intestinal microbiota following a dysbiosis caused by, among other... -
Antibiotic Resistances of Clostridioides difficile
The rapid evolution of antibiotic resistance in Clostridioides difficile and the consequent effects on prevention and treatment of C. difficile... -
Macrolides and Asthma Therapy
Asthma is a chronic condition of the airways that is typified by bronchial hyperresponsiveness, variable airflow obstruction, and airway... -
Macrolides in Chronic Skin Disorders
Macrolide antibiotics are widely used to treat infections of soft tissues and the respiratory tract due to their efficacy against Gram-negative and... -
Fecal Microbiota Transplantation as Emerging Treatment in European Countries 2.0
Clostridioides difficile infection (CDI) is one of the most common healthcare-associated infections and one of the leading causes of morbidity and...