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Effects of Sex Steroids on Innate and Adaptive Immunity
Estrogens and androgens are classically recognized as reproductive sex steroid hormones because of their well-documented effects on reproductive... -
Post-traumatic Epilepsy and Neuropsychiatric Comorbidities
Post-traumatic epilepsy (PTE) is a form of acquired epilepsy that arises from traumatic brain injury (TBI). It presents a complex relationship with... -
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Identification of Host Factors of Paramyxoviruses by siRNA Genome-Wide Screens
Measles is a highly infectious disease that continues to spread mainly in develo** countries, often resulting in child mortality. Despite the... -
Culturing Immortalized Human Airway Epithelial Cells at an Air-Liquid Interface for Measles Virus Infection
Measles virus (MeV) infection of airway surface epithelial cells provides a site for final amplification before being released back into the... -
Proximity Ligation Assay to Detect the Proximity Between Host Proteins and Viral Proteins of HIV-1
The study of host-pathogen interaction often requires interrogating the protein-protein interactions and examining post-translational modifications... -
Current Concepts and Advances in Oncobiology
Embarking on the dynamic landscape of oncology, this chapter navigates the interface between emerging concepts and transformative advancements in... -
Point of Care Molecular Diagnostics in Cancer
Among the major challenges facing the clinical applications of point of care (PoC) devices is to enable rapid, accurate, convenient, and... -
Strategies of Early Diagnosis of Cancers
When cancer is identified early, the chances of survival improve. However, almost half of all malignancies are identified at an advanced stage. Early... -
Tumor Heterogeneity in Breast Cancer Progression
Cancer is an aberrant growth of cells with dynamic molecular changes as the disease progresses. As a result of these dynamic changes and an increase... -
Molecular Pathways in Breast Cancer Chemoresistance
Chemoresistance is one of the determinants of breast cancer (BrCA) prognosis. Chemoresistance leads to recurrence and metastasis that causes adverse... -
Structuring Inflammasome-Epigenome: Phenotypic Axis in Gynecological Cancers
Inflammasomes are made up of sensor proteins, caspase domain having adaptor protein, and caspase-1 aka pro-inflammatory caspase present in the... -
Metabolic Syndrome as Forecast of Cancer
Evidences in literature are suggestive of strong influence of metabolic syndrome (MetS) and its components on cancer incidence, development, and its... -
Mitochondrial Quality Measures in the Regulation of Tumor Progression and Metastasis
Mitochondria are positioned as a crucial cell organelle with many decisive functions. Both the lifesaving energy requirement of a cell and cell death... -
Recent Advancements in the Inhibition of Metastasis of Colorectal Cancer Using Anticancer Compounds
Colorectal cancer (CRC) is the second most common cancer with a high mortality rate. CRC is a multistep process that begins with genetic and... -
Challenges and Future Directions of Anticancer Molecules and Their Delivery
Cancer cells proliferate indefinitely and destroy surrounding normal tissues which makes major threats to human health. According to WHO studies,... -
Putting a Magnifying Lens on Pharmacogenetics and Pharmacogenomics Associated Challenges and Opportunities in Area of Cancer Research
In cancer research, pharmacogenetics and pharmacogenomics are develo** fields that have the capability to have a huge impact on cancer healthcare... -
Chronology of Anticancer Drugs and Their Development
Chemotherapeutic drugs, or anticancer, are the chemical components which are used to treat cancer. The term anticancer drugs evolved in the era of... -
Polysaccharide-Based Nano-delivery Systems for the Treatment of Colorectal Cancer
Use of nano-delivery systems for the treatment of colorectal cancer has been tried successfully for almost all known varieties of such delivery... -
Molecular Analysis of Copy-Back Defective Interfering RNAs of Morbilliviruses
Copy-back defective interfering RNAs are major contaminants of viral stock preparations of morbilliviruses and other negative strand RNA viruses....