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    Chapter

    Genetic Engineering Strategies for Hematologic Malignancies

    Hematologic malignancies have several features that make them particularly well suited for treatment with the use of genetic engineering approaches. First, genetic engineering of stem cells can enhance the res...

    Thomas J. Kipps in Genetic Engineering (2000)

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    Chapter

    Genetic adjuvants for DNA immunization

    The injection of naked plasmid DNA expression vectors into animal muscle or skin has been shown to be an effective means to stimulate cellular and humoral immunity against the expressed protein [36]. However, ...

    Robert B. Mendoza, Thomas J. Kipps in Gene Vaccination: Theory and Practice (1998)

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    Chapter

    DNA vaccines with rapid intracellular degradation are more effective for inducing CTL

    DNA vaccines have several advantages over conventional vaccines, such as ease of construction, low expense for mass production, high temperature stability, and ability to induce a full spectrum of exceptionall...

    Yunqi Wu, Thomas J. Kipps in Gene Vaccination: Theory and Practice (1998)