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Etiology, Pathogenesis, and Genetics of Parkinson’s Disease
Parkinson’s disease (PD) is the second most common neurodegenerative disease after Alzheimer’s disease. Recent scientific interest has been focused on the molecular mechanism of nigral neuronal death and how t...
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Chapter
Ubiquitin-Proteasome Pathway is a Key to Understanding of Nigral Degeneration in Autosomal Recessive Juvenile Parkinson’s Disease
In most patients with Parkinson’s disease (PD), the contribution of genetic and environmental factors remains to be elucidated. The importance of genes in PD was controversial for many years. It has become cle...