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  1. No Access

    Chapter and Conference Paper

    Involvement of multiple survival signal transduction pathways in the neuroprotective, neurorescue and APP processing activity of rasagiline and its propargyl moiety

    Our recent studies aimed to elucidate the molecular and biochemical mechanism of actions of the novel anti-Parkinson’s drug, rasagiline, an irreversible and selective monoamine oxidase (MAO)-B inhibitor and it...

    Dr. O. Weinreb, T. Amit, O. Bar-Am, Y. Sagi… in Parkinson’s Disease and Related Disorders (2006)

  2. No Access

    Chapter

    Rapid Leaching Procedures — Possibilities and Limits

    On-site investigations are expected to give fast information on the hazardous potential of soil or landfill material. While most of the common field analytical methods will measure the total contamination a so...

    S. Mandel, A. Maurer, E. Kohlmeier in Field Screening Europe 2001 (2002)

  3. No Access

    Chapter and Conference Paper

    cDNA microarray to study gene expression of dopaminergic neurodegeneration and neuroprotection in MPTP and 6-hydroxydopamine models: implications for idiopathic Parkinson’s disease

    cDNA microarray membranes comprising 1,200 different gene fragments have been employed to identify gene expression profile in MPTPinduced nigro striatal dopamine neurodegeneration and its protection with R-apo...

    S. Mandel, E. Grünblatt, M. Youdim in Advances in Research on Neurodegeneration (2000)

  4. No Access

    Chapter and Conference Paper

    Iron chelating, antioxidant and cytoprotective properties of dopamine receptor agonist; apomorphine

    There have been many attempts to discover neuroprotective drugs for the treatment of Parkinson’s disease (PD). Many ofthese compounds either do not cross the blood brain barrier or are not very effective in th...

    Prof. M. B. H. Youdim, M. Gassen, A. Gross… in Advances in Research on Neurodegeneration (2000)

  5. No Access

    Chapter and Conference Paper

    Potent neuroprotective and antioxidant activity of apomorphine in MPTP and 6-hydroxydopamine induced neurotoxicity

    Apomorphine is a potent radical scavenger and iron chelator. In vitro apomorphine acts as a potent iron chelator and radical scavenger with IC50 of 0.3 μM for iron (2.5 μM) induced lipid peroxidation in rat brain...

    E. Grünblatt, S. Mandel, M. Gassen… in Advances in Research on Neurodegeneration (1999)

  6. No Access

    Chapter

    Hydrology of Arid Zones

    The term water crop denotes the resources of liquid water (surface water as well as groundwater) that are generated by precipitation at more or less regular intervals. The part of the hydrologic cycle that genera...

    S. Mandel in Arid Zone Irrigation (1973)