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    Chapter

    Viral Oncolysis of Glioblastoma

    The current state of replication-competent or replication-selective oncolytic viral treatment of malignant astrocytomas is reviewed. This includes studies examining the DNA viruses herpes simplex type I and ad...

    Dipongkor Saha, Robert L. Martuza, William T. Curry Jr. in Neurotropic Viral Infections (2016)

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    Chapter and Conference Paper

    Experimental Therapy for Malignant Brain Tumors Using Genetically Engineered Herpes Simplex Virus Type 1

    We are exploring a novel experimental treatment for malignant brain tumors utilizing a genetically engineered, attenuated, replication-competent herpes simplex virus type 1 (HSV-1). Our previous studies demons...

    Toshihiro Mineta, Samuel D. Rabkin, Robert L. Martuza in Brain Tumor (1996)

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    Chapter

    Virus-Mediated Genetic Treatment of Rodent Gliomas

    The most common primary central nervous system neoplasm in adults is the malignant glioma. Approximately 5,000 new cases are diagnosed annually in the United States. This tumor has proven to be extremely refra...

    E. Antonio Chiocca, Julie K. Andersen, Yoshiaki Takamiya… in Gene Therapeutics (1994)

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    Chapter

    Genetic Alterations of Nervous System Tumors

    The last decade has witnessed revolutionary advances in our understanding of the basic molecular changes associated with carcinogenesis in general and with nervous system tumorigenesis in particular. This repo...

    Robert L. Martuza in Biological Aspects of Brain Tumors (1991)