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    Chapter

    Mutational Profile of HPV-Positive HNSCC

    This chapter summarizes the mutational profile of head and neck squamous cell cancer (HNSCC) associated with infection of the human papillomavirus (HPV). Focusing on next-generation sequencing studies, the dif...

    Hua Li, Jennifer R. Grandis in Human Papillomavirus (HPV)-Associated Oropharyngeal Cancer (2015)

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    Chapter

    Chromatin Remodeling and Androgen Receptor-Mediated Transcription

    It has become apparent that the expression of human genes in chromatin is regulated by post-translational structural changes in histones, which form the major protein component of nucleosomes in chromatin. The...

    Li Jia, Omar Khalid, Baruch Frenkel in Androgen Action in Prostate Cancer (2009)

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    Chapter

    Images of Cleavage: Tumor Proteases in Action

    The roles of proteases in cancer are now known to be much broader than simply degradation of extracellular matrices during tumor invasion and metastasis. Furthermore, proteases from tumor-associated cells (e.g...

    Dr. Kamiar Moin, Mansoureh Sameni, Christopher Jedeszko, Quanwen Li in The Cancer Degradome (2008)