279 Result(s)
within
Chapter
Qi** Li
Chemistry
Inorganic Chemistry
Medicinal Chemistry
-
Chapter
Camps quinoline synthesis
Base-catalyzed intramolecular condensation of a 2-acetamido acetophenone (1) to a 2-(and possibly 3)-substituted-quinolin-4-ol (2), a 4-(and possibly 3)-substitutedquinolin-2-ol (3), or a mixture.
-
Chapter
Nenitzescu indole synthesis
5-Hydroxylindole from condensation of p-benzoquinone and β-aminocrotonate.
-
Chapter
Gewald aminothiophene synthesis
Base-promoted aminothiophene formation from ketone, αa-active methylene nitrile and elemental sulfur.
-
Chapter
Strecker amino acid synthesis
Sodium cyanide-promoted condensation of aldehyde, or ketone, with amine to afford α-amino nitrile, which may be hydrolyzed to α-amino acid.
-
Chapter
Tebbe’s reagent
The Tebbe’s reagent, μ-chlorobis(cyclopentadienyl)(dimethylaluminium)- μmethylenetitanium, transforms a carbonyl compound to the corresponding exoolefin.
-
Chapter
Dieckmann condensation
The Dieckmann condensation is the intramolecular version of the Claisen condensation.
-
Chapter
Doebner quinoline synthesis
Three-component coupling of an aniline, pyruvic acid, and an aldehyde to provide a quinoline-4-carboxylic acid.
-
Chapter
Barton radical decarboxylation
Radical decarboxylation via the corresponding thiocarbonyl derivatives of the carboxylic acids.
-
Chapter
Lawesson’s reagent
2,4-Bis(4-methoxyphenyl)-1,3-dithiadiphosphetane-2,4-disulfide transforms the carbonyl groups of aldehydes, ketones, amides, lactams, esters and lactones into the corresponding thiocarbonyl compounds. Cf. Knorr t...
-
Chapter
Reissert indole synthesis
The Reissert indole synthesis involves base-catalyzed condensation of an onitrotoluene derivative with an ethyl oxalate, which is followed by reductive cyclization to an indole-2-carboxylic acid derivative.
-
Chapter
Robinson–Gabriel synthesis
Cyclodehydration of 2-acylamidoketones to give 2,5-di- and 2,4,5-trialkyl, aryl, heteroaryl-, and aralkyloxazoles.
-
Chapter
Allan–Robinson reaction
Synthesis of flavones or isoflavones by the treatment of of o-hydroxyaryl ketones with aromatic aldehydes. Cf. Kostanecki reaction on page 322.
-
Chapter
Carroll rearrangement
Thermal rearrangement of β-ketoesters followed by decarboxylation to yield γunsaturated ketonesvia anion-assisted Claisen rearrangement. It is a variant of the Claisen rearrangement (page 117).
-
Chapter
Chapman rearrangement
Thermal aryl rearrangement of O-aryliminoethers to amides.
-
Chapter
Nysted reagent
The Nysted reagent, cyclo-dibromodi-з -methylene(з-tetrahydrofuran)trizinc, is used for the olefination of keton%-s and aldehydes.
-
Chapter
Gassman indole synthesis
The Gassman indole synthesis involves a one-pot process in which a hypohalite, a β-carbonyl sulfide derivative, and a base are added sequentially to an aniline or a substituted aniline to provide 3-thioalkoxyi...
-
Chapter
Gomberg–Bachmann reaction
Base-promoted radical coupling between an aryl diazonium salt and an arene to form a diaryl compound.
-
Chapter
Thorpe–Ziegler reaction
The intramolecular version of the Thorpe reaction, which is base-catalyzed self-condensation of nitriles to yield imines that tautomerize to enamine.
-
Chapter
Dötz reaction
Cr(CO)3-coordinated hydroquinone from vinylic alkoxy pentacarbonyl chromium carbene (Fischer carbene) complex and alkynes.
-
Chapter
Barton nitrite photolysis
Photolysis of a nitrite ester to a γ-oximino alcohol.
