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    Chapter

    Adipose Tissue-Resident Regulatory T Cells

    Tissue-resident immune cells play critical roles in regulating tissue function and homeostasis. Obesity-associated visceral adipose tissue inflammation is attributed to the accumulation of M1 macrophages which...

    Fuxiang Zhu, Aiting Wang, Yangyang Li, Rui Liang… in Immune Metabolism in Health and Tumor (2017)

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    Chapter

    Regulation of Metabolism Across Different Subsets of T Cells in Cancer

    T cells play a critical role to defend against tumor and maintain immune homeostasis. The diverse functions of T cells require precise regulation of metabolic pathways. Recent studies reveal that metabolic cha...

    Xuerui Luo, Fuxiang Zhu, Zuojia Chen, Dan Li… in Immune Metabolism in Health and Tumor (2017)

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    Chapter

    Transcriptional Regulation of T Cell Metabolism Reprograming

    T cell activation, differentiation, and function are tightly regulated by a complex network of transcription factors, epigenetic modifications, and signaling pathways of both TCR and cytokines. Over the past d...

    **xia Zhang, Guoyu Bi, Yu **a, **fei Li… in Immune Metabolism in Health and Tumor (2017)

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    Chapter

    Immune Cell Metabolism in Tumor Microenvironment

    Tumor microenvironment (TME) is composed of tumor cells, immune cells, cytokines, extracellular matrix, etc. The immune system and the metabolisms of glucose, lipids, amino acids, and nucleotides are integrate...

    Yongsheng Li, Yisong Y. Wan, Bo Zhu in Immune Metabolism in Health and Tumor (2017)