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Chapter
Strategies to Optimize Peptide Stability and Prolong Half-Life
Peptide drugs represent 5% of the global pharmaceutical market, but growing twice as fast as the rest of the drug market. The development of peptide therapeutics is challenging due to their low stability, shor...
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Chapter
Overview of the Impact of Protein Interfacial Instability on the Development of Biologic Products
Interfacial phenomena can significantly affect the development, manufacturing, stability, and use of therapeutic proteins. Proteins are exposed to air-liquid, solid-liquid, and liquid-liquid interfaces through...
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Chapter
Future Perspectives
In this chapter, we describe future perspectives of product development of biologics with an emphasis on the effect of interfacial stress on product performance and development, including analytical detection,...