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    Chapter

    Strategies to Optimize Peptide Stability and Prolong Half-Life

    Peptide drugs represent 5% of the global pharmaceutical market, but growing twice as fast as the rest of the drug market. The development of peptide therapeutics is challenging due to their low stability, shor...

    Sophia M. Shi, Li Di in Peptide Therapeutics (2022)

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    Chapter

    Overview of the Impact of Protein Interfacial Instability on the Development of Biologic Products

    Interfacial phenomena can significantly affect the development, manufacturing, stability, and use of therapeutic proteins. Proteins are exposed to air-liquid, solid-liquid, and liquid-liquid interfaces through...

    **jiang Li, Mary E. Krause, Raymond Tu in Protein Instability at Interfaces During D… (2021)

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    Chapter

    Future Perspectives

    In this chapter, we describe future perspectives of product development of biologics with an emphasis on the effect of interfacial stress on product performance and development, including analytical detection,...

    **jiang Li… in Protein Instability at Interfaces During Drug Product Development (2021)