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    Chapter

    Diseases of DNA Polymerase Gamma

    Polymerase gamma (Polγ) is the DNA-dependent DNA polymerase responsible for replicating mitochondrial DNA. The enzyme is a trimer and comprises one catalytic subunit (POLG), which contains the polymerase activ...

    Omar Hikmat, Pirjo Isohanni, Anu Suomalainen in Diagnosis and Management of Mitochondrial … (2019)