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Chapter and Conference Paper
Significance of Lineage-Associated Transcripts of TdT and ETS1 for Detection of Leukemic Cells
One approach for a rational postremission therapy of acute leukemia is based on detection of residual leukemic blasts. Immunophenoty** with monoclonal antibodies, quantitative DNA analysis for aneuploidy, PC...
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Chapter
The Mammalian ETS Genes: Two Unique Chromosomal Locations in Cat, Mice and Man and Novel Translocated Position in Human Leukemias
The ets sequence was identified as a second cellular sequence transduced by the avian replication-defective retrovirus, E26. The 5.7-kilobase (kb) RNA genome of E26 contains: in addition to partial retroviral gag
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Chapter
Adenosine Deaminase and Terminal Transferase in Leukemic Cells
The characterization of leukemic blasts has been recently greatly improved by the use of biochemical markers, such as Terminal deoxynucleotidyl Transferase (TdT) and Adenosine Deaminase (ADA).
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Chapter
Disappearance of Nuclear TdT in RPMI-8402 Following TPA Treatment
Terminal deoxynucleotidyl transferase (TdT) is a useful marker to study T-cell ontogeny and more generally lymphocyte differentiation.
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Chapter
Effect of Nucleosides on Human T and B Lymphoblastoid Cell Lines
Human T and B lymphoblastoid cell lines have been used as model systems to study the biochemical basis of some immune disfunctions, associated to specific purine metabolic enzyme deficiencies (1,2).
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Chapter
Clinical Relevance of Terminal Transferase and Adenosine Deaminase in Leukemia
Terminal Transferase (TdT), Adenosine Deaminase (ADA), immunological membrane markers, cytochemical reactivity and cytogenetics were analyzed in 226 patients with ALL, AUL and AML, in 70 patients with CML and ...
