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Mantle Cell/Centrocytic Lymphoma: Molecular and Phenotypic Analysis Including Analysis of the bcl-1 Major Translocation Cluster by PCR
Mantle cell/centrocytic lymphoma (MCL) is a biologically and clinically distinct subtype of non-Hodgkin’s lymphoma (NHL) characterized by small lymphocytes with irregular nuclei and a diffuse, vaguely nodular,...
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Centrocytic Lymphoma: a B-Cell Non-Hodgkin’s Lymphoma Characterized by Chromosome 11 BCL-1 and PRAD 1 Rearrangements
Centrocytic lymphoma is a CD5-positive B cell neoplasm defined in the Kiel classification (Figure 1) [1]. This lymphoma, composed of cells resembling centrocytes (cleaved follicular center cells), is distingui...