24 Result(s)
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Chapter
Autophagy in Muscle Stem Cells
, also known , are responsible for the regenerative capacity of adult muscle tissue in response to stress and injury. Upon regenerative stimuli, satellite cells are activated and undergo myogenic commitment. ...
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Chapter
IGF Genes in Golden Pompano Trachinotus ovatus Larvae
Insulin-like growth factors (IGFs) include IGF I and IGF II. IGF I is an essential regulator of cell division, differentiation, embryonic development, and growth. IGF II, also known as somatomedin A, is mainly...
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Chapter
Intestinal Fatty Acid-Binding Protein Gene (I-FABP) in Golden Pompano Trachinotus ovatus Larvae
Fatty acid-binding proteins (FABPs) belong to the multigene family with 14–16 kDa molecular mass and have the function of binding long-chain fatty acids in both vertebrates and invertebrates. The intestinal fa...
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Chapter
Endothelial Cell Dynamics during Blood Vessel Morphogenesis
Blood vessels, together with the heart, have a fundamental role in supporting the metabolic demands of tissues not only during development but also in adults. New blood vessels are frequently generated through...
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Chapter
Editing Cultured Human Cells: From Cell Lines to iPS Cells
The human genome is complex, and the functions of many genes and specific genomic elements have not been fully explored. Cultured human cells, from conventional cell lines to iPS cells, are valuable tools that...
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Chapter
Plasticity of Airway Lymphatics in Development and Disease
The dynamic nature of lymphatic vessels is reflected by structural and functional modifications that coincide with changes in their environment. Lymphatics in the respiratory tract undergo rapid changes around...
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Chapter
Regulatory T-Cell Differentiation and Their Function in Immune Regulation
Regulatory T-cells (Treg) represent a subset of CD4+ T-cells characterized by high suppressive capacity, which can be generated in the thymus or induced in the periphery. The deleterious phenotype of the Scurf...
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Chapter and Conference Paper
S-RNase-Based Self-Incompatibility in Petunia: A Complex Non-Self Recognition System Between Pollen and Pistil
Self-incompatibility (SI) is an intraspecific reproductive barrier that allows many families of flowering plants to prevent inbreeding and promote outcrosses. Extensive studies of SI in five families during th...
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Chapter
The Dynamics of Neuronal Migration
Proper lamination of the cerebral cortex is precisely orchestrated, especially when neurons migrate from their place of birth to their final destination. The consequences of failure or delay in neuronal migrat...
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Chapter
Functional Multipotency of Neural Stem Cells and Its Therapeutic Implications
In this review, we propose an updated concept of the neural stem cell (NSC). New data of our own and others suggest that the field’s conventional view which has touched principally on the essential multipotenc...
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Chapter
Actin-based Chromosome Movements in Cell Division
Although microtubules are well-studied players moving chromosomes during mitosis and meiosis, recent work in mammalian oocytes has revealed intricate interactions between actin and chromosomes that directly co...
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Chapter
Formin-Mediated Actin Assembly
Formins are remarkable large multi-domain proteins that utilize a novel mechanism to rapidly assemble actin filaments for diverse cellular processes such as division, motility, polarity, stress fibers and foca...
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Chapter
Intermediate Filament Expression in Mouse Embryonic Stem Cells and Early Embryos
In this work we discuss the expression of intermediate filament protein and synthesis in mouse oocytes and preimplantation murine embryos. Also we touch to epithelial differentiation and intermediate-sized fil...
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Chapter
Epithelial Stem Cells and the Development of the Thymus, Parathyroid, and Skin
It is evident that epithelial tissues are able to self-renew not only during normal homeostasis but also following damage. How this occurs has major implications for the development of therapies for degenerati...
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Chapter
Cyclin-Dependent Kinase 5 (Cdk5) Modulates Signal Transduction Pathways Regulating Neuronal Survival
Cyclin-dependent kinase 5 (Cdk5) in the nervous system has evolved to become a “surveillance system” that, among its other functions, monitors and integrates fluctuations in the activities of signaling cascade...
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Chapter
Cdk5 May Be an Atypical Kinase, but Not in the Way You Think
Cyclin-dependent kinase 5 (Cdk5) is a non-traditional CDK. It relies on two specific activators––p35 and p39––that are structurally similar to cyclins but genetically distinct. Analysis of the Cdk5 knockout (o...
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Chapter
Cyclin-Dependent Kinase 5 (Cdk5): Linking Synaptic Plasticity and Neurodegeneration
It is well established that cyclin-dependent kinase 5 (Cdk5) is critically involved in neurodevelopmental processes. In addition, recent data point toward an important role of Cdk5 in regulating synaptic plast...
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Chapter and Conference Paper
Cotton 14-3-3L Gene Is Preferentially Expressed in Fiber
14-3-3 protein was originally identified during a systematic classification of bovine brain proteins. Thereafter, a number of 14-3-3 proteins have been found in every eukaryotic organism such as animal, fungi,...
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Chapter and Conference Paper
Inositol Polyphosphate 6-/3-kinase (AtIpk2β), an Early Auxin-Responsive Gene, Positively Regulates Axillary Shoot Branching in Arabidopsis thaliana
Arabidopsis inositol polyphosphate 6-/3-kinase gene (AtIpk2β) has previously been demonstrated to participate in inositol phosphate metabolism. However, overall little is known about its physiological functions i...
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Chapter and Conference Paper
An Arabidopsis Nudix Hydrolase Modulates the Innate Immune Response Independent of NPR1 and Salicylate
Plants have evolved complicated systems to regulate immune responses. The innate immune response which is triggered following recognition of conserved microbe-associated molecular patterns (MAMPs) provides the...
