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    Chapter

    Nanodesigned Pore-Containing Systems for Biosensing and Controlled Drug Release

    For medical treatment of disease, optimal therapeutic efficiency of a drug is governed by both the therapeutic activity of the drug itself and the way in which it is delivered to the patient. Once administered...

    Frédérique Cunin, Yang Yang Li, Michael J. Sailor in BioMEMS and Biomedical Nanotechnology (2007)

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    Chapter

    Microscale Flow and Transport Simulation for Electrokinetic and Lab-on-Chip Applications

    The proliferation of manufacturing techniques for building micro- and nano-scale fluidic devices has led to a virtual explosion in the development of microscale chemical and biological analysis systems, common...

    David Erickso, Dongqing Li in BioMEMS and Biomedical Nanotechnology (2007)

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    Chapter

    BioMEMS for Cellular Manipulation and Analysis

    Since the introduction of Micro-electro-mechanical systems in the early 70’s, the significance of the biomedical applications of these miniature systems has been realized [54, 77]. BioMEMS, the abbreviation for B...

    Haibo Li, Rafael Gómez-Sjöberg, Rashid Bashir in BioMEMS and Biomedical Nanotechnology (2007)

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    Chapter

    Evaluation of the Reliability of cDNA Microarray Technique

    Yao Li, Yao Luo, Chengzhi Zhang, Minyan Qiu, Zhiyong Han in Frontiers in Biochip Technology (2006)

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    Chapter

    Fast Screening of Single-Nucleotide Polymorphisms Using Chip-Based Temperature Gradient Capillary Electrophoresis

    Recently, the analysis of single-nucleotide polymorphisms has attracted much attention. Although many techniques have been reported, new methods with high resolving power, low-cost and fast speed are still in ...

    Peng Liu, Wan-Li **ng, Dong Liang, Guo-Liang Huang in Frontiers in Biochip Technology (2006)

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    Chapter

    Photoactivatable Silanes: Synthesis and Uses in Biopolymer Array Fabrication on Glass Substrates

    We wish to report a fast and easy way to build hydrophobic layers and hydrophilic functional polymer layers thereafter onto glass surfaces. A benzophenone-based silane was synthesized and used to prepare stabl...

    Handong Li, Glenn Mcgall in Frontiers in Biochip Technology (2006)

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    Chapter

    An Integrated Biochemoinformatics System for Drug Discovery

    Chipscreen Biosciences, Ltd. (www.chipscreen.com) is a drug discovery company specialized in novel small molecule therapeutics. Chipscreen has developed a proprietary chemical genomics approach to accelerate t...

    Leming Shi, Zhenqiang Su, Aihua **e, Chenzhong Liao in Frontiers in Biochip Technology (2006)

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    Chapter

    Cellular to Tissue Informatics: Approaches to Optimizing Cellular Function of Engineered Tissue

    Tissue engineering is a rapidly expanding, multi-disciplinary field in biomedicine. It provides the ability to manipulate living cells and biomaterials for the purpose of restoring, maintaining, and enhanc...

    Sachin Patil, Zheng Li, Christina Chan in Tissue Engineering I (2006)

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    Chapter

    Electronic Biosensors Based on DNA Self-Assembled Monolayer on Gold Electrodes

    Information concerning the immobilization and hybridization of DNA on a surface is paramount to the development of DNA-based electronic biosensors. This study looks at recent investigations of DNA immobilized ...

    Chen-Zhong Li, Yi-Tao Long, Todd Sutherland in Frontiers in Biochip Technology (2006)

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    Chapter

    Improvement of Microarray Technologies for Detecting Single Nucleotide Mismatch

    With the completion of the Human Genome Project and beginning of post genome era, there is an urgent need for a fast, specific, sensitive, reliable and cost-effective method for the genome-wide polymorphism an...

    Hong Wang, Zuhong Lu, Jiong Li, He** Liu, Quanjun Liu in Frontiers in Biochip Technology (2006)

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    Chapter

    Biomolecular Sensing for Cancer Diagnostics Using Carbon Nanotubes

    The field of biomolecule sensing in the medical field is broad and rapidly evolving. The devices range in size from microns to centimeters across the sensing surface and rely on electronic, optical or other fo...

    Jun Li, M. Meyyappan in BioMEMS and Biomedical Nanotechnology (2006)

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    Chapter

    NMR Spectroscopy of Tumors

    Magnetic resonance imaging is widely employed in the clinical detection of cancer. Discrimination of tumors from surrounding normal tissues is based on differences in relaxation times, which are usually longer...

    J. D. Glickson, J. P. Wehrle, S. S. Rajan in NMR: Principles and Applications to Biomed… (1990)