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    Chapter

    Immune Evasive Stem Cell Islets

    Type 1 diabetes (T1D) is an autoimmune disease caused by the destruction of insulin-secreting β cells by the immune system (American Diabetes, A., Diabetes Care 32 Suppl 1:S62–67, 2009). It is characterized by...

    Federica Cuozzo, Valeria Sordi in Pluripotent Stem Cell Therapy for Diabetes (2023)

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    Chapter

    Bioengineered Vascularized Insulin Producing Endocrine Tissues

    Islet transplantation is a promising treatment for type 1 diabetes (T1D), but limited islet engraftment hampers its success. In vivo, islets require time to remodel the hepatic parenchyma and establish their o...

    Francesco Campo, Alessia Neroni in Pluripotent Stem Cell Therapy for Diabetes (2023)