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Immune Evasive Stem Cell Islets
Type 1 diabetes (T1D) is an autoimmune disease caused by the destruction of insulin-secreting β cells by the immune system (American Diabetes, A., Diabetes Care 32 Suppl 1:S62–67, 2009). It is characterized by...
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Chapter
Bioengineered Vascularized Insulin Producing Endocrine Tissues
Islet transplantation is a promising treatment for type 1 diabetes (T1D), but limited islet engraftment hampers its success. In vivo, islets require time to remodel the hepatic parenchyma and establish their o...