23 Result(s)
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Chapter
In the Pipeline: Emerging Therapy for CML
The development of BCR-ABL1 tyrosine kinase inhibitors (TKI) has revolutionized the treatment of CML. A major limitation of TKI therapy is the relative inability to eradicate quiescence CML leukemic stem cells...
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In the Pipeline: Emerging Therapy for MDS and MDS/MPN
Novel agents in combination with hypomethylating agents are an emerging strategy for clinical trials in involving higher-risk MDS or MDS/MPN and in patients harbouring high-risk mutations such as those involving
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Optimising Breast Screen Reading Efficacy
The aim of early detection of disease is to facilitate the delivery of a treatment to those with no or minor symptoms whilst avoiding harm to those who do not need treatment. However, the balance of benefits a...
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Design of Nanostructure Materials to Modulate Immunosuppressive Tumour Microenvironments and Enhance Cancer Immunotherapy
Cancer immunotherapy uses host’s inherent immune system to treat cancer and imparts a memory effect on the immune system that can inhibit cancer relapse. However, due to the complexity and diversity of the imm...
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MRI Characteristics
Although radiographs remain the mainstay for initial assessment and diagnosis of bone tumors, magnetic resonance imaging may aid in further characterizing non-mineralized matrix of the tumor. Collagenous strom...
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Basic Concepts and Diagnostic Parameters
Accurate radiological diagnosis of bone tumors is based on a systematic and organized analysis of the clinical and radiographic features. Factors to be considered include clinical factors such as the age and g...
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Osteoclastic Giant Cell-Rich Tumors
Giant cell-rich lesions encompass a wide range of lesions that are characterized by the presence of numerous multinucleated osteoclast-like giant cells. A wide spectrum of diseases may fall into this category,...
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Vascular Tumors
Vascular tumors of the bone include various tumors ranging from benign lesions to malignancies. Hemangioma of the bone is the most common benign vascular tumor of the bone. Angiosarcomas of the bone are malign...
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Tumor Syndromes
A large number of hereditary and non-hereditary syndromes are associated with an increased risk of bone tumors. The diagnosis of some of these syndromes may be made based on the imaging findings: enchondromato...
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Radiographic Findings
The radiographic features that narrow the differential diagnosis include patterns of bone destruction, lesion margins, matrix of the lesion, location, site, and type of host bone response. Bone tumors can be c...
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Cases
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List the differential diagnoses of this condition.
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Fibrogenic and Fibrohistiocytic Tumors
Fibrous tumors are characterized by the presence of fibrous content (collagen) and can be divided into fibrogenic tumors and fibrohistiocytic tumors. Fibrogenic tumors are characterized by the production of co...
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Hematopoietic Neoplasms and Small Round Cell Tumors
Hematopoietic neoplasms comprise a wide variety of diseases including myeloproliferative neoplasms, myelodysplastic syndromes, acute leukemia, and lymphomas that may exhibit overlap** imaging features. In th...
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Other Tumor-Like Lesions and Soft Tissue Type Tumors
A wide variant of non-tumorous bone lesions may exhibit radiographic and MRI features similar to neoplastic conditions of the bone. The World Health Organization classification includes simple bone cysts, aneu...
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Chondrogenic Tumors
Chondroid matrix is seen in lesions comprised of chondrocyte proliferation. The radiographic appearance can be described as ring-and-arc, punctate, curved, stippled, or coarser flocculent foci of calcification...
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Chapter
Role of Nutrition in Oral and Pharyngeal Cancers: From Etiology to Prevention
Oral and pharyngeal cancers (OPC) are highly prevalent tumors and rank as the sixth most common neoplasms. Some dietary factors have been linked to increased risk of OPC such as consumption of red meats and sa...
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Osteogenic Tumors
The matrix of a bone lesion refers to the acellular material produced by the mesenchymal cells composing the lesion. Although many bone lesions produce no matrix, its presence can indicate the predominant cell...
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Extrahepatic Bile Duct Carcinoma: Role of the p53 Protein Family
Bile duct carcinomas (cholangiocarci-noma) are devastating tumors. Surgical resection is the mainstay of current treatment; however, it is only effective for a limited number of patients diagnosed at early sta...
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Biologie, l’essentiel pour le clinicien
Les papillomavirus humains (HPV) appartiennent à une famille de virus récemment reconnue et appelée Papillomaviridae. On distingue des virus à tropisme cutané et des virus à tropisme muqueux. Parmi les HPV muqueu...
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Chapter
Cytoreduction and Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis of Ovarian Cancer
