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    Chapter

    Cytokines in the Treatment of Cancer

    Cytokines are molecular mediators of intercellular signaling that function to regulate homeostasis of the immune system. There are five families of cytokines classified by their receptor usage. The effects of ...

    Kim Margolin, Mark Lazarus, Howard L. Kaufman in Cancer Immunotherapy (2013)

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    Chapter

    Fluorouracil and Leucovorin in Advanced Breast Cancer

    It is clear from the studies summarized above that the combination of leucovorin and 5-FU can salvage 15–20% of heavily-pretreated patients with advanced breast cancer. In previously-untreated patients, the co...

    James H. Doroshow, Kim Margolin in Novel Approaches to Selective Treatments o… (1993)