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    Chapter

    Alternative Strategies for the Production of an Antibody-Cytokine Fusion Protein from Recombinant BHK Cells

    The choice of scale up strategies for production of recombinant proteins from animal cells is often restricted to suspension cultures in stirred tank bioreactors. The primary aim of the work reported here was ...

    D. Looby, J. L. Moreira, G. N. Stacey, H. Cruz, M. Cuffe, E. Dias… in Animal Cell Technology (1997)

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    Chapter

    Evaluation of a Porous Silicone Carrier (Immobasil G) for Animal Cell Culture

    Porous carriers can be used in fixed, fluidised and stirred tank perfusion culture systems, where high unit cell density and good scale-up potential can be combined with longterm continuous operation (1 and 2)...

    D. Looby, A. J. Racher, J. P. Fuller… in Animal Cell Technology: Developments Towar… (1995)

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    Cultural and physiological factors affecting expression of recombinant proteins

    The variability in expression of recombinant proteins has been analyzed with regard to (a) comparison of clones from the same transfection experiment; (b) comparison of the same genetic construct in different ...

    J. B. Griffiths, A. J. Racher in Cell Culture Engineering IV (1995)

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    Chapter

    Recombinant Antibody Expression in a Fixed Bed Perfusion System

    Process parameters affecting the productivity of a fixed bed bioreactor (FBR) system, based on Siran beads, have been studied. A recombinant BHK21 cell line was grown with different combinations of process par...

    A. J. Racher, J. B. Griffiths in Animal Cell Technology: Basic & Applied Aspects (1994)