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Chapter
Monocyte Chemotactic Peptide-1 (Mcp-1) and NAP-1/IL-8 Formation in Baboon Septicemia are Partially TNF Dependent
Cytokines like IL-1 and IL-6 are released in sepsis in a TNF dependent manner. Therefore we asked the question, whether TNF might be responsible for MCP-1 and NAP-1 production in baboon septicemia (2 hours inf...
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Chapter and Conference Paper
The Role of TNF in Gram-Negative Sepsis in Baboon
During sepsis TNF message is expressed and the protein is released both locally and into plasma. Teleologically such cytokine response must be beneficial to the host. However, from a certain threshold level of...
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Chapter and Conference Paper
Trauma and Cytokines
Trauma still constitutes the most frequent cause of death in the first four decades of life and ranks third over all age brackets (Baker et al. 1980, Baue 1990, Chaudry et al. 1990, National Safety Council 198...
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Chapter
Experiments with Kainate and Quisqualate Agonists and Antagonists in Relation to the Sub-Classification of ‘Non-NMDA’ Receptors
The differentiation of “kainate” (K) and “quisqualate” (Q) sub-classes of non-NMDA excitatory amino acid (EAA) (Davies et al., 1979; Watkins, 1978) receptors was originally based on the selective depressant ac...
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Chapter
Recent Advances in the Pharmacology of Excitatory Amino Acids in the Mammalian Central Nervous System
Current ideas are described on the classification of excitatory amino acid receptors in the mammalian central nervous system. The actions of some new agonists and antagonists for NMA receptors and non-NMA rece...