6 Result(s)
within
Biomedicine
Oncology
Hua **a
Chapter
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Chapter
Targeting p53-MDM2-MDMX Loop for Cancer Therapy
The tumor suppressor p53 plays a central role in anti-tumorigenesis and cancer therapy. It has been described as “the guardian of the genome”, because it is essential for conserving genomic stability by preven...
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Chapter
Assessment of Diagnostic Tests and Instruments
Assessment of accuracy and reliability of screening tests such as detection of cancer and depression is important in clinical and research studies. Although a diagnostic test may not be accurate, the criteria ...
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Chapter
Applications of Human Induced Pluripotent Stem Cell Derived Hepatocytes
Human induced pluripotent stem cells (iPSCs) are potential sources of hepatocytes for drug development and cell therapy. In vitro differentiation of iPSCs into hepatic cells has been achieved and improved duri...
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Chapter
NF1 Gene: Promoter, 5′ UTR, and 3′ UTR
The NF1 gene has a TATA-less promoter with a classic CpG island and a 454-bp 5′ untranslated region (UTR). The CpG island is normally unmethylated, with the gene actively transcribed in all tissues examined to da...
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Chapter and Conference Paper
Characterization of Antioxidative Peptides from Soybean Proteins
Protease hydrolyses of various proteins yielded antioxidative activity against the peroxidation of linoleic acid. From the hydrolysate of a soybean protein, six antioxidative peptides were isolated by size exc...
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Chapter and Conference Paper
Changes in Protein Expression During Oval Cell Proliferation in the Liver
Two-dimensional Polyacrylamide gel electrophoresis (2DE) is a powerful technique for separation of proteins. This technology can now be used for analysis of protein expression and variation, and for identifica...
