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    Chapter

    mTOR Signaling in Angiogenesis

    An important feature of tumor blood vessels is that they are in a state of constant new tumor blood vessel growth. In endothelial cells, the PI3K/Akt pathway has been shown to play an important role in mediati...

    Henry Mead, Mirjana Zeremski, Markus Guba in mTOR Pathway and mTOR Inhibitors in Cancer… (2010)