7 Result(s)
within
Gene Therapy
Ben Ep**er
Chapter
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Chapter
Restriction Fragment Length Polymorphism of HLA-DR7 Alleles and Association with HLA-B Antigens
Although HLA-DR7 appears to be serologically homo- 2. geneous (1), it may be split according to epitopes recognized by T cells (Dw7, Dwl1) and is normally found in association with either DQw2 or DQw3. This re...
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Identification of Dw2, Dw12, and “Short” DR2 Splits with Sequential Exon-Specific DRβ, DQβ, and DQα cDNA Probes
The HLA-DR2 specificity has been divided by alloantisera (DR2 and “short” DR2) and by T cells (Dw2, Dw12, DB9 (LD-5a), FJO, and LD-MN2). The FJO and LD-MN2 splits appear to correlate with the short DR2 serotyp...
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Nucleic Acids-Based Therapeutics in the Battle Against Pathogenic Viruses
For almost three decades, researchers have studied the possibility to use nucleic acids as antiviral therapeutics. In theory, compounds such as antisense oligonucleotides, ribozymes, DNAzymes, and aptamers can...
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Gene Therapy Strategies to Block HIV-1 Replication by RNA Interference
The cellular mechanism of RNA interference (RNAi) plays an antiviral role in many organisms and can be used for the development of therapeutic strategies against viral pathogens. Persistent infections like the...
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Chapter
Correction to: Application of iPSC to Modelling of Respiratory Diseases
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Chapter
Application of iPSC to Modelling of Respiratory Diseases
Respiratory disease is one of the leading causes of morbidity and mortality world-wide with an increasing incidence as the aged population prevails. Many lung diseases are treated for symptomatic relief, with ...
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CRISPR-Cas-Based Gene Therapy to Target Viral Infections
In recent years, there is an increasing demand for the development of new antiviral strategies due to the prevalence of viral infections such as those caused by the human immunodeficiency (HIV) or the hepatiti...
