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Chapter and Conference Paper
Localization of Phospholipids in Plasma Membranes of Mammalian Cells
A transversal, asymmetric distribution of phospholipids is characteristic for most membrane systems investigated so far. Following a period in which an inventory was made of the asymmetry in various membrane s...
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Chapter and Conference Paper
Recognition and Elimination of Malaria-Infected Erythrocytes by a Modified Phospholipase A
The erythrocyte plays an essential role in a particular part of the complex life cycle of Plasmodium, the malaria causing parasite, when it serves as a host cell in which the parasite feeds, grows and multipli...
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Chapter and Conference Paper
Phospholipid Localization and Mobility in Plasmodium Infected Erythrocytes
Upon infection of erythrocytes with Plasmodium, the malaria causing parasite, the red cell membrane undergoes a variety of changes. Proteins, encoded by the parasitic DNA are inserted into the membrane (Howard...
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Chapter
The Interaction of Pancreatic Phospholipase A2 with Negatively Charged Substrates — Application: The Transformation of Soluble Phospholipase A2 into a Highly Penetrating “Membrane-Bound” Form
This study deals with some kinetic properties of porcine pancreatic phospholipase A2 (PLA2) acting on neutral and anionic substrates. Short—chain diacylglycerosulfates possess a much higher affinity to the enzyme...
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Chapter
Two-Dimensional Thin Layer Chromatography. Separation of Lipids Extracted from Native and Phospholipase A2 Treated Human Erythrocyte Ghosts
Qualitative and quantitative analyses of (phospho)lipids play an important role in studies on the structure and function of biological membranes. Even the investigator who is primarily interested in the protei...
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Chapter and Conference Paper
Some Aspects of the Ca-Pump in Human Red Blood Cells
HRBCs are endowed with a membrane-bound system which extrudes Ca2+ ions against a large gradient from the cytosol to the medium (Schatzmann, 1966; Schatzmann and Vincenzi, 1969; Lee and Shin, 1969; Olson and Cazo...
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Chapter
Lipoprotein Integrity and Enzymatic Activity of the Erythrocyte Membrane
In the last few years, a variety of methods for solubili-zing proteins from erythrocyte stroma have appeared in the literature. Nearly all depend on: i) detergent action, in some cases combined with acidic or ...