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  1. No Access

    Chapter

    Epidemiology of Cancer

    Over 19 million new cancer cases lead to almost ten million deaths globally in 2020. The most common cancers worldwide are breast and lung cancers, while prostate cancer is the most common in the male populati...

    Hui-Yi Lin, Jong Y. Park in Anesthesia for Oncological Surgery (2023)

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    Chapter

    The Role of Epigenetics in Brain and Spinal Cord Tumors

    Identification of distinct genetic profiles in has improved the classification and uncovered novel diagnostic, prognostic, and predictive molecular biomarkers for improved prediction of treatment response ...

    Sung-Hye Park in Human Brain and Spinal Cord Tumors: From Bench to Bedside. Volume 1 (2023)

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    Chapter

    Leveraging Tissue Engineering for Skin Cancer Models

    Bioengineered in vitro three-dimensional (3D) skin model has emerged as a promising tool for recapitulating different types of skin cancer and performing pre-clinical tests. However, a full-thickness 3D model ...

    Sumayah Oudda, Abdulla M. Ali, Anna L. Chien in Cell Biology and Translational Medicine, V… (2023)

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    Chapter

    Bone Sarcoma

    While relatively rare, primary bone sarcomas are associated with high morbidity and mortality. A comprehensive history, examination, and imaging work-up should be performed in any suspected bone sarcoma. Percu...

    Akash A. Shah, Howard Y. Park in Cancer Metastasis Through the Lymphovascul… (2022)

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    Chapter

    High-Risk Population Based on BC Risk Factors

    Breast cancer (BC) is the second leading cause of female cancers worldwide in 2018, followed by lung cancer, and the fifth fatal cancer, followed by lung, colorectal, gastric, and liver cancers. The incidence ...

    Sue K. Park, Keun-Young Yoo in Translational Research in Breast Cancer (2021)

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    Chapter

    Clinical and Practical Recommendations in the Use of Exercise, Physical Therapy, and Occupational Therapy for Chemotherapy-Induced Peripheral Neuropathy

    Chemotherapy-induced peripheral neuropathy (CIPN) is a highly prevalent, severe, and dose-limiting toxicity of several chemotherapy regimens for the treatment of multiple cancers including lung, breast, prosta...

    Ian R. Kleckner, Susanna B. Park in Diagnosis, Management and Emerging Strateg… (2021)

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    Chapter

    Care for Breast Cancer Survivors

    The number of cancer survivors is increasing globally. More than 15.5 million Americans in 2016 and 1.3 million Koreans in 2013 were living with cancer history. This growing population is expected to increase ...

    Su Min Jeong, Sang Min Park in Translational Research in Breast Cancer (2021)

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    Chapter

    Single Cell Genomics for Tumor Heterogeneity

    Single cell genomics became a universal and powerful tool to study cellular diversity at genomic levels in normal and disease conditions. Cancer is a disease of genomic instability which instigates clonal evol...

    Hae-Ock Lee, Woong-Yang Park in Translational Research in Breast Cancer (2021)

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    Chapter

    Systematic Review of Exercise for Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy

    Chemotherapy-induced peripheral neuropathy (CIPN) is a highly prevalent and dose-limiting toxicity of many widely used chemotherapy regimens for the treatment of common cancers including lung, breast, prostate...

    Ian R. Kleckner, Susanna B. Park in Diagnosis, Management and Emerging Strateg… (2021)

  10. Chapter

    The Heterogeneity of Lipid Metabolism in Cancer

    The study of cancer cell metabolism has traditionally focused on glycolysis and glutaminolysis. However, lipidomic technologies have matured considerably over the last decade and broadened our understanding of...

    Joshua K. Park, Nathan J. Coffey, Aaron Limoges in The Heterogeneity of Cancer Metabolism (2021)

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    Chapter

    Adiponectin in Gastrointestinal Malignancies

    Obesity and its related metabolic deregulation have poor prognosis for several cancers, including gastric cancer (GC) and colorectal cancer (CRC). Adiponectin (also known as adipoQ, Acrp30, GBP-28, and apM1) s...

    Batoul Farran, Iffat Zahin Atiquah in Novel therapeutic approaches for gastroint… (2020)

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    Chapter

    Gastric Cancer and Its Remedy

    Gastric cancer or stomach cancer is a very harmful disease in which malignant cells grow in the tissues of the stomach at an uncontrolled rate. It is one of the most prevalent malignant diseases with one of th...

    Abdul Alim, Rokshana Sharmin, Dongkyoo Park in Novel therapeutic approaches for gastroint… (2020)

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    Chapter

    Natural Agents Mediated Regulation of microRNAs: Do We Need Skilled Archers to Hit the Bullseye

    MicroRNAs (miRNAs) are short noncoding RNAs, which control gene expression by messenger RNA degradation or translational repression. MicroRNAs are also reportedly involved in regulation of carcinogenesis, angi...

    Eun Jung Sohn, Ammad Ahmad Farooqi in Recent Trends in Cancer Biology: Spotlight… (2018)

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    Chapter

    Plant Cell and Organ Culture as an Alternative for the Production of Anticancer Compounds

    Plants are the reservoirs of various valuable secondary metabolites like camptothecin, podophyllotoxin, and ginseng saponins which are used as anticancer agents. Plant cell and organ cultures are competent to ...

    Hosakatte Niranjana Murthy in Anticancer Plants: Natural Products and Bi… (2018)

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    Chapter

    The Heterogeneity of Lipid Metabolism in Cancer

    The study of cancer cell metabolism has traditionally focused on glycolysis and glutaminolysis. However, lipidomic technologies have matured considerably over the last decade and broadened our understanding of...

    Joshua K. Park, Nathan J. Coffey, Aaron Limoges in The Heterogeneity of Cancer Metabolism (2018)

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    Chapter

    Enrichment and Detection of Circulating Tumor Cells and Other Rare Cell Populations by Microfluidic Filtration

    The current standard methods for isolating circulating tumor cells (CTCs) from blood involve EPCAM-based immunomagnetic approaches. A major disadvantage of these strategies is that CTCs with low EPCAM expressi...

    Michael Pugia, Mark Jesus M. Magbanua in Isolation and Molecular Characterization o… (2017)

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    Chapter

    Role of STAT3 in Liver Cancer

    Hepatocellular carcinoma (HCC) is a malignant cancer that shows heterogeneous etiology and the third leading of cancer-related deaths in the world. In spite of its severity, there is only one systemic chemothe...

    Dongkyoo Park, Neha Merchant, Inho Choi in Role of Transcription Factors in Gastroint… (2017)

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    Chapter

    Circulating Free Tumor DNA (ctDNA): The Real-Time Liquid Biopsy

    It is now well established that DNA is shed or secreted into the circulation in both normal and disease states. However, the ability to exploit this knowledge for use in clinical medicine has only recently bee...

    Kelly Kyker-Snowman, Ben Ho Park in Liquid Biopsies in Solid Tumors (2017)

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    Chapter

    Role of Hypoxia-Inducible Factor (HIF) in Liver Cancer

    Liver cancer is one of the major causes of cancer-related deaths in the United States, accounting for 4.5% of the total estimated cancer deaths in 2016 and standing as the second leading cause of cancer-relate...

    Inho Choi, Saipriya Lammata, Neha Merchant in Role of Transcription Factors in Gastroint… (2017)

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    Chapter

    Osmolytes Offset the Urea’s Effect on Protein Structure and Function

    High concentrations of urea are accumulated intracellularly in marine elasmobranchs and inner medullary region of mammalian kidney. It has been found that methylamine organic osmolytes are accumulated in conce...

    Safikur Rahman, Jihyun Park, Jihoe Kim in Cellular Osmolytes (2017)

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