362 Result(s)
within
English
Life Sciences
**hu Zhu
Chapter
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Chapter and Conference Paper
A Novel Dual Interactive Network for Parkinson’s Disease Diagnosis Based on Multi-modality Magnetic Resonance Imaging
Parkinson’s disease is a neurodegenerative disorder that often leads to abnormal atrophy in certain brain regions. Due to the ability to display brain structures non-invasively, magnetic resonance imaging (MRI...
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Chapter and Conference Paper
RabbitSAlign: Accelerating Short-Read Alignment for CPU-GPU Heterogeneous Platforms
Short-read alignment is a critical, yet time-consuming step in many next-generation sequencing data analysis pipelines. Most approaches follow the seed-and-extend strategy, where seeding usually involves a lar...
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Chapter and Conference Paper
Multi-scale Mean Teacher for Unsupervised Cross-Modality Abdominal Organ Segmentation with Limited Annotations
The achievement of Deep Convolutional Neural Networks (DCNNs) in abdominal organ segmentation can be attributed to the availability of extensive annotated data. Unsupervised Domain Adaptation (UDA) has been de...
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Policy Learning for Individualized Treatment Regimes on Infinite Time Horizon
With the recent advancements of technology in facilitating real-time monitoring and data collection, “just-in-time” interventions can be delivered via mobile devices to achieve both real-time and long-term man...
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Small RNA and DNA Methylation of Tea Plants
Small RNAs are a category of short noncoding RNAs (ncRNAs) with 18–30 nt lengths. Based on their function and mechanisms of biogenesis, these small RNAs be classified into three major classes—microRNAs (miRNAs...
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Host Plant Resistance to Insects in Cotton
Across the globe, cotton production is limited by endemic and introduced insect pests. The incorporation of host plant resistance (HPR), defined as the ability of a plant to defend itself against targeted biot...
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Chemotaxonomy and Genomes
Chemotaxonomy or chemical taxonomy is the identification and classification of an organism based on the differences or similarities of the chemical features present in the cell structure such as peptidoglycan ...
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Nutrition, Epigenetics, and Circadian Rhythms
Most organisms adapt to the 24-h cycle of the Earth’s rotation by anticipating the time of day through light–dark processes. The biological clock is crucial for the survival of living organisms and environment...
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Chapter and Conference Paper
On Sorting by Flanked Transpositions
Transposition is a well-known genome rearrangement event that switches two consecutive segments on a genome. The problem of sorting permutations by transpositions has attracted a great amount of interest since...
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Synthetic Biology: Safety Issues
Safety issues are the key issues for the healthy development of synthetic biology. The generation of novel life forms, biosafety, and biosecurity are the three main ethical issues of synthetic biology. Regulat...
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Chapter and Conference Paper
HetBiSyn: Predicting Anticancer Synergistic Drug Combinations Featuring Bi-perspective Drug Embedding with Heterogeneous Data
Synergistic drug combination is a promising solution to cancer treatment. Since the combinatorial space of drug combinations is too vast to be traversed through experiments, computational methods based on deep...
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Chapter and Conference Paper
NeoMS: Identification of Novel MHC-I Peptides with Tandem Mass Spectrometry
The study of immunopeptidomics requires the identification of both regular and mutated MHC-I peptides from mass spectrometry data. For the efficient identification of MHC-I peptides with either one or no mutat...
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Research in China and International Research
The classic definition of epigenetics is “the study of changes in gene function that are heritable but do not entail a change in DNA sequence.” The epigenetic phenomenon was first observed in Drosophila melanogas...
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Outlook
Epigenetics has emerged since the late 1980s. In the twenty-first century, with advances in technological means, this new discipline is develo** in an unprecedentedly rapid speed. Increasingly more biophysic...
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Chapter and Conference Paper
A Convolutional Denoising Autoencoder for Protein Scaffold Filling
De novo protein sequencing is a valuable task in proteomics, yet it is not a fully solved problem. Many state-of-the-art approaches use top-down and bottom-up tandem mass spectrometry (MS/MS) to sequence prote...
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Project Overview
The Major Research Plan of “Epigenetic Mechanisms of Cell Programming and Reprogramming” (hereinafter referred to as “this MRP”) was launched by the National Natural Science Foundation of China (NSFC) during t...
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Rejuvenation and Regenerative Potential of Heart Stem Cells
Cardiovascular diseases, more precisely myocardial infarction, are the leading cause of mortality on a global scale resulting in a widespread loss of functional cardiomyocytes. Thus, the ability to regenerate ...
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Microbial Interaction in Chinese Liquor Fermentation
Microbial communities are more than the sum of their members, because of the complex microbial ecological interactions in the community. Understanding the types and mechanism of microbial interactions is essen...
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Bridge the Channel, Enhance the Inclusivity: A Comparison Between Flagship Species-Centered and Moss-Centered Conservation in Chile and China
I contrast flagship species-centered approach and moss-centered approach in biological conservation. The context I conduct this research is the status quo of contemporary ecological sciences and communication....
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PKCβII–ACSL4 Axis Triggers Ferroptosis and Its Potential Implication in Ferroptosis-Related Diseases
Ferroptosis is a regulated cell death process independent of apoptosis, triggered by excessive peroxidation of polyunsaturated fatty acids (PUFAs) in the presence of iron. This mode of cell death is closely li...
