113 Result(s)
within
English
Electronics and Microelectronics, Instrumentation
Engineering, general
Pharmacy
**e **an
Chapter
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Chapter and Conference Paper
Photothermal Ultrasensitive Detection and Microchemistry in the Integrated Chemistry Lab
Non-fluorometric and non-electrophoretic lab-on-chip was realized with utilizing thermal lens microscopy for ultrasensitive detection and diffusion phenomenon for molecular transport. Thermal lens microscope, ...
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Chapter and Conference Paper
Microfabricated Chips for Capillary Electrophoresis on Quartz Glass Substrates Using a Bonding with Hydrofluoric Acid
Fabrication method and characteristics of micro capillary electrophoresis (μ-CE) chips fabricated on synthetic fused silica (quartz glass) substrates are described. A novel room temperature bonding method with...
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Chapter and Conference Paper
Computer Simulations for Microchip Electrophoresis
A mathematical model describing electrokinetically driven mass transport phenomena in microfabricated chip devices is presented. The model accounts for principal material transport mechanisms including electro...
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Chapter and Conference Paper
Use of Surfactant Additives for Modification of Electroosmotic Flow and Wall Chemistry
Addition of the zwitterionic surfactant CAS U to an electrophoretic buffer prevents interaction between cationic proteins and the capillary channel walls. It allows quantitative recovery of the proteins and yi...
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Chapter and Conference Paper
Free Flow Electrophoresis Module Fabricated with Pyrex Glass
In this study a free flow electrophoresis (FFE) module was constructed as a preparatory unit of the system to separate DNA from other contaminants in the specimens. The FFE module was made from Pyrex glass to ...
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Chapter and Conference Paper
Integrated Serial Dilution on a Microchip for Immunoassay Sample Treatment and Flow Injection Analysis
This paper presents the design and performance of two serial diluters, a 32-fold diluter performing 1:1 dilution in 5 steps and a 1024-fold diluter with ten 1:1 mixing intersections. The simulation package SPI...
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Chapter and Conference Paper
Development of a Microfabricated Biochemical Workbench — Improving the Mixing Efficiency —
Unlike the existing μTAS, we have tried to conduct cell-free translation on a chip as the first step toward the highly automated biochemical microsystems named, “Micro Work Bench”. This paper describes the det...
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Chapter and Conference Paper
Characterization of Silicon-Based Insulated Channels for Capillary Electrophoresis
A new fabrication method to produce miniaturized Transparent Insulating Channels (μTICs) is presented. The process involves Deep Reactive Ion Etching (DRIE), insulating film deposition, anodic bonding and back...
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Chapter and Conference Paper
Microfabricated Dual-Microdialysis and Capillary Isoelectric Focusing Devices for Cleanup and Separations / Mass Spectrometric Analysis of Biomolecules
A laser microfabricated device was constructed for rapid on-line microdialysis cleanup of biological samples for analysis by electrospray ionization mass spectrometry (ESI-MS). Efficient desalting was achieved...
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Chapter and Conference Paper
Liquid Mixing Studies with an Integrated Mixer/Valve
This work presents the design, fabrication, and testing of an integrated mixer/valve and a method for determining its mixing performance. The method correlates the mixing time to a quantitatively measurable ob...
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Chapter and Conference Paper
Continuous Flow Versus Stopped flow in A Micro flow Injection System
The effects of continuous, pulsed and stopped flow on the dispersion of a dye in a micro flow injection system were studied experimentally and by digital simulation. A channel of 200 μm by 200 μm by 21550 μm w...
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Chapter and Conference Paper
Micro-Analytical (μFIA) Reactor for the Determination of Phosphate as Orthophosphate
Sample preparation and measurement procedures that are currently performed in modern analytical laboratory facilities, can be scaled down to a device of a few sq.cm. 1,2. Such a device often employs electroosmoti...
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Chapter and Conference Paper
Electrokinetic Generation of High Pressures using Porous Microstructures
The ability to generate high pressures using electrokinetic pum** of liquid through porous media is reported. Pressures in excess of 8000 psi have been achieved using silica capillaries packed with micron-si...
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Chapter and Conference Paper
Numerical Simulation of Magnetic Separation of Particles in a Rectangular Microchannel
In this paper we present a numerical simulation of the motion of magnetically labeled cells exposed to a magnetic force. The results show that optimal separation of labeled cells from nonlabeled cells requires...
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Chapter and Conference Paper
Micro-Fluidic Diffusion Coefficient Measurement
A new method for diffusion coefficient measurement applicable to micro-fluidics is presented. The method utilizes an analytical model describing laminar dispersion in rectangular micro-channels. The method was...
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Chapter and Conference Paper
Applying Microfluidic Chemical Analytical Systems to Imperfect Samples
Over the last 4 years our group has been involved in develo** a series of devices for chemical separation and analysis. These devices share a theme of utilizing the low Reynolds number properties of liquids ...
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Chapter and Conference Paper
Isotachophoresis on Planar Polymeric Substrates
The work presented here describes the design, fabrication, evaluation and use of miniaturised polymeric devices, for performing capillary isotachophoresis (CITP). CITP is an electrophoretic separation method t...
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Chapter and Conference Paper
An Electronic Nose Based on A Micromechanical Cantilever Array
We present a novel chemical sensor based on a micromechanical array of silicon cantilevers sensitized for the detection of analytes using cantilever coatings such as metals, self-assembled monolayers, or polym...
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Chapter and Conference Paper
Automatic Sensor System for Water Analysis
An automatic sensor system based on micromachined components has been realized for groundwater monitoring. The system operates automatically in a suspended multisensor probe under water and includes fluidic ac...
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Chapter and Conference Paper
Individual Embryo Transport and Retention on a Chip
We have designed, built, and tested a micro fluidic system capable of transporting individual, pre-implantation mouse embryos through a network of channels to selected locations. The flow of buffer causes the ...
