386 Result(s)
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Materials Science
Molecular Medicine
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Applications
3D skin equivalents were one of the first TE organs used for clinical trials. In early skin were incorporated into a to mimic the dermal matrix. Since then, the evolution of scaffolds for skin cell cultu...
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Introduction
The human skin is the largest organ in our body and serves as and interface between the body and the environment. Our skin interacts with various stimuli while maintaining a homeostatic balance. When this ba...
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Bioengineered Skin Substitutes
The skin can self-renew, thanks to the presence of stem cells in . However, when the skin is damaged in the deeper layers, as in second or , the responses are impeded, resulting in a chronic injury.
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Commercial Skin Equivalents
In the last decades, regenerative medicine has undergone a significant transformation, largely due to advances in skin TE, driven primarily by large commercial companies.
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Conclusions
The translation of tissue engineering concepts into the development of biomimetic skin models is a growing trend that began as a treatment strategy to save and improve patients’ quality of life. As summarized ...
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Skin Physiology and Function
The skin is the largest organ of the body (it accounts for about 15% of total body weight in adults) and, together with its derived structure, forms the integumentary system. As the body's outermost layer, the...
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Growing Skin-Like Tissue
Skin substitutes offer new therapeutic options for treating acute and chronic skin wounds.
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Crosslinking Strategies to Develop Hydrogels for Biomedical Applications
Hydrogels can be defined as the networks of either chemically or physically crosslinked hydrophilic polymers containing large amounts of water when hydrated. They are usually used as biomaterials for various a...
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Surface Chemistry and Properties of Magnetic Nanoparticles
Magnetic nanoparticles have gained considerable attention among the scientific community because of its wide range of potential applications in diversified fields. Due to the above reason, most of the research...
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Nanobased Biodegradable Hydrogel for Biomedical Application
Recently, the design of hydrogels using bio-based materials has been increasingly developed for application in pharmaceutical technology. The incorporation of nanoscale structures is useful for tuning the cell...
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Magnetic and Fluorescent Nanogels for Nanomedicine
The field of nanomedicine has been expanding rapidly in the recent decades that opened the current century. Specifically, nanogels comprise an interesting subset of the nanomedicine design space. A brief overv...
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Polymer–Water Interactions in Hydrogels
Hydrogels are water/polymer systems that are in high demand due to their broad-spectrum applications in the industrial and bio-medical sectors. A basic hydrogel is a polymer network capable of absorbing a larg...
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Magnetic Nanoparticles for Hyperthermia a New Revolution in Cancer Treatment
Magnetic nanoparticles are an important class of nanomaterials. Several types of magnetic nanoparticles have been discovered in the recent years. The major mechanism of action of magnetic nanoparticles in canc...
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Cross-Linking, Modular Design and Self-assembly in Hydrogels
Gels can be recognised as a stiff but flexible, soft everyday material. They survive the “inversion test”, it is solid-like rheology that defies the character of the gel. Low-molecular-weight gels can be class...
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Hydrogel Formulation as Efficient Drug Carrier and Delivery for Selected Skin Diseases
During the last a few decades, the rapid proliferation in the prevalence of skin diseases has been a major unease for healthcare providers, and it is currently regarded as a global encumbrance and reflected as...
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Elasticity, Strength, and Biocompatibility of Hydrogels
Hydrogels have been a familiar term in the current biomedical research. Generally, hydrogels are swollen polymer networks with water. Biocompatibility and ease of preparation are the key properties which enabl...
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Biomaterials and Its Advances for Delivering Anticancer Drugs
Most of the anticancer drugs affect both the cancerous cells and the normal cells. The most common treatment chemotherapy is always associated with the poor selection of the targeted cancer cells and also the ...
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Self-assembled Hydrogels: An Overview
Self-assembled hydrogels are a three-dimensional network of polymeric materials that are self-assembled either by physical or chemical crosslinking. Excellent biocompatibility, biodegradability, and sensitivit...
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Hybrid Nanoparticles in Image-Guided Drug Delivery
The recent advancements in nanotechnology have opened immense opportunities for the management several clinical complications. The multidisciplinary approach of combining drug delivery and image-guided diagnos...
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Novel Biocompatible Hydrogels via Click Chemistry
Currently, the designing and development of advanced hydrogel platforms is one of the important research areas due to their applications in the fabrication of functionalized materials useful in biomedical scie...
