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    Chapter

    The Crystal Structure of Mitochondrial Cytochrome bc 1 Complex

    The cytochrome bc 1 complex (commonly known as ubiquinol-cytochrome c reductase, or complex III) is a segment of the mitochondrial respiratory chain that catalyzes antimycin-sensitive electron transfe...

    Chang-An Yu, Li Zhang, Anatoly M. Kachurin in Frontiers of Cellular Bioenergetics (1999)

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    Chapter

    Iron in mammals: pathophysiological mechanisms of overload and deficiency in relation to disease

    The uptake of iron into the body is tightly regulated in humans and in other mammals. Mutations in key proteins that transport, sense, metabolize, and facilitate the utilization of iron cause perturbations in ...

    Martha B. Johnson, Caroline A. Enns in Molecular Biology of Metal Homeostasis and… (2006)

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    Chapter

    Reconstruction and Structural Analysis of Metabolic and Regulatory Networks

    Networks of interacting cellular components carry out the essential functions in living cells. Therefore, understanding the evolution and design principles of such complex networks is a central issue of system...

    Hong-wu Ma, Marcio Rosa da Silva, Ji-Bin Sun in Introduction to Systems Biology (2007)

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    Chapter

    Fidelity Mechanisms of the Aminoacyl-tRNA Synthetases

    The central dogma and its accurate interpretation by a large array of biomolecules remains a fascinating process. Understanding its mechanisms of decoding holds tremendous potential for the future of protein e...

    A. P. Mascarenhas, S. An, A. E. Rosen, S. A. Martinis in Protein Engineering (2009)

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    Chapter

    Modeling of Intracellular Transport and Compartmentation

    The complexity and internal organization of mammalian cells as well as the regulation of intracellular transport processes has increasingly moved into the focus of investigation during the past two decades. Ad...

    Uwe Jandt, An-** Zeng in Genomics and Systems Biology of Mammalian Cell Culture (2012)

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    Chapter

    Role of DJ-1 in Fertilization

    Neither a sperm nor an egg can develop into an individual alone. Only when the sperm and egg bind and fuse, which is known as fertilization, can they acquire the ability of develo** into new individuals. DJ-...

    An Chunna, **ao-** Pu in DJ-1/PARK7 Protein (2017)

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    Chapter

    Targeting Bone Marrow-Derived Fibroblasts for Renal Fibrosis

    Renal fibrosis is a major pathological feature of chronic kidney disease, which is characterized by massive fibroblast activation and excessive production and deposition of extracellular matrix (ECM). Renal fi...

    Changlong An, Li Jia, Jia Wen, Yanlin Wang in Renal Fibrosis: Mechanisms and Therapies (2019)