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Cullin-RING Ligases and Protein Neddylation Biology and Therapeutics
This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go...
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Epigenetics in Allergy and Autoimmunity
This book will address the growing roles of epigenetics in disease pathogenesis, and review the contribution of epigenetic modifications to disease...
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Histone Deacetylase Inhibitors — Epidrugs for Neurological Disorders
This book provides an outline of epigenetics as a whole, while also specifically examining a range of epigenetic players, including histone acetyl...
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The Biology of mRNA: Structure and Function
The book provides an overview on the different aspects of gene regulation from an mRNA centric viewpoint, including how mRNA is assembled and...
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Mycobacterium Tuberculosis: Molecular Infection Biology, Pathogenesis, Diagnostics and New Interventions
This book reviews recent advances in the molecular and infection biology, pathology, and molecular epidemiology of Mycobacterium tuberculosis, as...
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Insights into Human Neurodegeneration: Lessons Learnt from Drosophila
This book is aimed at generating an updated reservoir of scientific endeavors undertaken to unravel the complicated yet intriguing topic of...
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SUMO Regulation of Cellular Processes
This is the second edition of a very well received book that details how the sumoylation system functions and how it modulates numerous cellular...
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Regulation of Inflammatory Signaling in Health and Disease
This book discusses recent research in innate immunity, which has revealed a large number of receptors that sense the presence of microorganisms or...
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Immune Metabolism in Health and Tumor
This book offers a broad overview of the concepts and research findings in immunometabolism. The immune system is made up of numerous different cell...
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Protein Tyrosine Phosphatases in Cancer
This book aims to bridge the gap in understanding how protein-tyrosine phosphatases (PTPs), which carry out the reverse reaction of tyrosine...
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Histone Recognition
This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic...
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Nutrition, Exercise and Epigenetics: Ageing Interventions
This book focuses on the three most important aspects of ageing research: nutrition, physical exercise and epigenetics. The contributors discuss ways...
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Non-coding RNAs and Cancer
The discovery of microRNAs and its role as gene expression regulators in human carcinogenesis represents one of the most important scientific...
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Lipid Hydroperoxide-Derived Modification of Biomolecules
Lipid peroxidation is an important cellular process which can lead to detrimental effects if it is not regulated efficiently. Lipid hydroperoxide is...
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Vesicle Trafficking in Cancer
Endocytosis and vesicular trafficking determine the landscape of the cell’s exterior, namely the density of surface molecules, such as receptors for...
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Epigenetics: Development and Disease
Epigenetics is the phenomenon which fine tunes the processes associated with life, beyond that which is specified by the sequence of the genetic...
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Emerging Concepts of Tumor Exosome–Mediated Cell-Cell Communication
In multicellular organisms, communication between cells involves secretion of proteins that bind to receptors on neighboring cells. While this has...
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Histone Deacetylases: the Biology and Clinical Implication
The book highlights work from many different labs that taught us abnormal HDACs potentially contribute to the development or progression of many...
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Phosphodiesterases as Drug Targets
Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective...
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SUMO Regulation of Cellular Processes
Over a decade ago, a small cellular protein of 12 kDa, with 18% homology to the well-known ubiquitin protein, was co-discovered and termed Small...
