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Synovial calprotectin in prosthetic joint infection. A systematic review and meta-analysis of the literature
IntroductionCalprotectin is a protein endowed with antimicrobial properties, rendering it a distinctive marker for infection. Two methods are...
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[18F]-D3FSP β-amyloid PET imaging in older adults and alzheimer’s disease
Purpose[ 18 F]-D3FSP is a new β-amyloid (Aβ) PET imaging tracer designed to decrease nonspecific signals in the brain by reducing the formation of the...
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Does ponticulus posticus affect vertebral artery diameter
PurposePonticulus Posticus, atlantooccipital ligament ossification-induced anomaly, surrounds the vertebral artery and the first cervical nerve root....
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Evidence-based clinical practice guidelines for the management of acute ankle injuries according to: a PRISMA systematic review and quality appraisal with AGREE II
BackgroundAcute ankle injuries are commonly seen in emergency rooms, with significant social impact and potentially devastating consequences. While...
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Prospective investigation of amino acid transport and PSMA-targeted positron emission tomography for metastatic lobular breast carcinoma
PurposeTo explore the feasibility of imaging amino-acid transport and PSMA molecular pathways in the detection of metastatic breast invasive lobular...
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Biomechanically based Fu’s subcutaneous needling treatment for senile knee osteoarthritis: protocol for a randomized controlled trial
IntroductionFu’s subcutaneous needling (FSN) is a new type of acupuncture that uses subcutaneous tissue to oscillate from side to side to improve...
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Efficacy and safety of romosozumab: a meta-analysis of placebo-controlled trials
IntroductionWe aimed to comprehensively compile placebo-controlled trials on the efficacy and safety of romosozumab (210 mg, subcutaneously, once...
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Predicting brace holiday eligibility in juvenile idiopathic scoliosis
PurposeThe psychological effects of scoliosis bracing can be difficult, and thus clinicians sometimes recommend a brace holiday when the curve...
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Risk factors for false positive and false negative MRI in diagnosing medial and lateral meniscal tears with concomitant ACL injury
ObjectiveTo determine the diagnostic performance of MRI in evaluating meniscal abnormalities in the setting of anterior cruciate ligament (ACL)...
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A Canadian Retrospective Chart Review Evaluating Concomitant Methotrexate De-escalation Patterns in Patients with Rheumatoid Arthritis Treated with Biologic or Targeted Synthetic DMARDs
IntroductionRheumatoid arthritis (RA) guidelines recommend methotrexate (MTX)-anchored therapy with biologic or targeted synthetic disease-modifying...
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Age-adjusted Charlson Comorbidity Index as an effective tool for the choice between simultaneous or staged bilateral total knee arthroplasty
IntroductionThe choice between simultaneous and staged bilateral total knee arthroplasty (BTKA) remains controversial. Age-adjusted Charlson...
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Increased risk of hip and major osteoporotic fractures in 8463 patients who have undergone stem cell transplantation, a Swedish population-based study
SummaryIn this retrospective cohort study of adult stem cell transplanted patients ( n = 8463), a significant increased risk of both MOF and hip...
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Is still effective massive allograft reconstruction in parosteal osteosarcoma of the distal femur? Review of the literature and advantages of newer technologies
PurposeParosteal Osteosarcoma is a well-differentiated, low-grade bone sarcoma. It most commonly occurs in the third decade of life, usually in the...
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Mechanisms of osteoporosis associated with chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is a disease characterized by chronic respiratory symptoms due to inflammatory and destructive changes...
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Total-body dynamic PET/CT imaging reveals kinetic distribution of [13N]NH3 in normal organs
PurposeTo systematically investigate kinetic metrics and metabolic trap** of [ 13 N]NH 3 in organs.
MethodsEleven participants performed total-body [
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The Relationship between the complement system and subclinical carotid atherosclerosis in patients with rheumatoid arthritis
BackgroundPatients with rheumatoid arthritis (RA) have an increased risk of cardiovascular (CV) events and CV mortality. Subclinical carotid...
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Zervikale Stenose – Diagnostik und Therapie der symptomatischen Spinalkanalstenose und Neuroforamenstenose
Cervical stenosis is a clinical picture that is regularly encountered by both hospital physicians and orthopedic surgeons in the daily clinical...
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Preclinical evaluation of [18F]SYN1 and [18F]SYN2, novel radiotracers for PET myocardial perfusion imaging
BackgroundPositron emission tomography (PET) is now an established diagnostic method for myocardial perfusion imaging (MPI) in coronary artery...