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Power-law scaling in intratumoral microbiota of colorectal cancer
It has recently been proposed that the study of microbial dynamics in humans may gain insights from island biogeographical theory. Here, we test...
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The C-terminal proline-rich repeats of Enteropathogenic E. coli effector EspF are sufficient for the depletion of tight junction membrane proteins and interactions with early and recycling endosomes
BackgroundEnteropathogenic E. coli (EPEC) causes acute infantile diarrhea accounting for significant morbidity and mortality in develo**...
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New Variants Identified by Next-Generation Sequencing in Polycystic Kidney Disease Patients
Polycystic kidney disease (PKD) is a common inherited disease characterized by multiple cysts in kidneys and various extra renal manifestations....
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Equol: a metabolite of gut microbiota with potential antitumor effects
An increasing number of studies have shown that the consumption of soybeans and soybeans products is beneficial to human health, and the biological...
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Assessment of the influence of levees along Yangtze River on Oncomelania hupensis, the intermediate host of Schistosoma japonicum
BackgroundOncomelania hupensis is the exclusive intermediate host of Schistosoma japonicum in China. Snail control is an essential component of...
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Horizontal gene transfer of the Mer operon is associated with large effects on the transcriptome and increased tolerance to mercury in nitrogen-fixing bacteria
BackgroundMercury (Hg) is highly toxic and has the potential to cause severe health problems for humans and foraging animals when transported into...
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Human cytomegalovirus microRNAs: strategies for immune evasion and viral latency
Viruses use various strategies and mechanisms to deal with cells and proteins of the immune system that form a barrier against infection. One of...
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Cultivation of novel Atribacterota from oil well provides new insight into their diversity, ecology, and evolution in anoxic, carbon-rich environments
BackgroundThe Atribacterota are widely distributed in the subsurface biosphere. Recently, the first Atribacterota isolate was described and the...
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Impact of the COVID-19 pandemic on extended-spectrum β-lactamase producing Escherichia coli in urinary tract and blood stream infections: results from a nationwide surveillance network, Finland, 2018 to 2022
BackgroundBefore the COVID-19 pandemic there has been a constant increase in antimicrobial resistance (AMR) of Escherichia coli , the most common...
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Advancing Frontiers: Graphene-Based Nano-biosensor Platforms for Cutting-Edge Research and Future Innovations
Graphene and its derivatives have excellent electrical, mechanical, and optical capabilities, making it the perfect foundation for sensing living...
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GIS-based spatiotemporal map** of malaria prevalence and exploration of environmental inequalities
Malaria poses a significant threat to global health, with particular severity in Nigeria. Understanding key factors influencing health outcomes is...
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Management of patient with Fusobacterim nucletum related pleural empyema: intrapleural antibiotic therapy can be considered for salvage therapy
Pleural empyema can lead to significant morbidity and mortality despite chest drainage and antibiotic treatment, necessitating novel and minimally...
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Comparative genomics of quinolone-resistant Escherichia coli from broilers and humans in Norway
BackgroundThe usage of fluoroquinolones in Norwegian livestock production is very low, including in broiler production. Historically,...
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Evaluation of the in vitro activity of ampicillin-sulbactam and cefoperazone-sulbactam against A. Baumannii by the broth disk elution test
To evaluate the in vitro activity of ampicillin-sulbactam and cefoperazone-sulbactam against A. baumannii using the broth disk elution testing, a...
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A randomised trial of malaria vaccine R21/Matrix-M™ with and without antimalarial drugs in Thai adults
In preparation for mass vaccinations with R21/Matrix-M™ combined with mass administrations of dihydroartemisinin, piperaquine, and a single low dose...
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Development and validation of machine learning models to predict MDRO colonization or infection on ICU admission by using electronic health record data
BackgroundMultidrug-resistant organisms (MDRO) pose a significant threat to public health. Intensive Care Units (ICU), characterized by the extensive...
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Secondary attack rate following on-site isolation of patients with suspected COVID-19 in multiple-bed rooms
The implementation of isolation precautions for patients with suspected Coronavirus Disease 2019 (COVID-19) and pending test results is resource...
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Cryptococcus laurentii: a wild yeast for xylanase production from agricultural by-products
The development of technologies that allow the production of enzymes at a competitive cost is of great importance for several biotechnological...
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Obesity, abdominal obesity, metabolic obesity phenotypes, and Helicobacter pylori infection: results from NHANES 1999–2000
BackgroundRecent studies on the association between Helicobacter pylori ( H. pylori ) infection and obesity have reported conflicting results....
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CircFAM114A2 Suppresses Cell Proliferation, Migration, and Invasion of Colorectal Cancer Through Sponging miR-647 to Upregulate DAB2IP Expression
BackgroundIncreasing evidence had proved that some circular RNA (circRNA) exerted critical roles in tumors progression by functioning as “microRNAs...