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Functional and clinical roles of stromal PDGF receptors in tumor biology
PDGF receptors play pivotal roles in both developmental and physiological processes through the regulation of mesenchymal cells involved in paracrine...
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Skin carotenoid scores and metabolic syndrome in a general Japanese population: the Hisayama study
BackgroundHigher vegetable intake is being promoted as an initiative to prevent lifestyle-related diseases. Carotenoids are yellow or red pigment...
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Niclosamide modulates phenotypic switch and inflammatory responses in human pulmonary arterial smooth muscle cells
Excessive proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) represent key steps of pulmonary vascular remodeling,...
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Mediated effects of a randomised control trial for a text messaging smoking cessation intervention for online help-seekers and primary care visitors
Background and AimsDigital smoking cessation interventions have been shown to be effective in hel** individuals achieve prolonged smoking...
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Demographic changes in COVID-19 mortality during the pandemic: analysis of trends in disparities among workers using California’s mortality surveillance system
BackgroundThere is limited information on the extent and patterns of disparities in COVID-19 mortality throughout the pandemic. We aimed to examine...
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Predictive ability of the health belief model in HIV testing and counselling uptake among youth aged 15–24 in La-Nkwantanang-Madina Municipality, Ghana
BackgroundMajority of new Human Immunodeficiency Virus (HIV)-positive persons in Ghana are aged 15–24. HIV prevalence among persons aged 15–24 years,...
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Implementing a free lending of sports and leisure equipment service: a cross-sectional survey exploring user characteristics, utilization patterns, and significance among children and youth
BackgroundThe escalating costs of sports equipment, coupled with socioeconomic disparities, hinder children’s participation in physical activities....
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Recursive partitioning analysis for survival stratification and early imaging prediction of molecular biomarker in glioma patients
BackgroundGlioma is the most common primary brain tumor with high mortality and disability rates. Recent studies have highlighted the significant...
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Analysis of tumor abnormal protein expression and epidermal growth factor receptor mutation status in non-small cell lung cancer
BackgroundThe level of tumor abnormal protein (TAP) level has a significant impact on tumor growth, recurrence, and metastasis. Previous studies have...
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Analysis of the characteristics, efficiency, and influencing factors of third-party mediation mechanisms for resolving medical disputes in public hospitals in China
BackgroundMedical disputes, which are prevalent in China, are a growing global public health problem. The Chinese government has proposed third-party...
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Prevalence and risk factors of human papilloma virus infection among women living with HIV, Egypt, a cross sectional study
BackgroundHPV is considered the most common sexually transmitted infection. It is responsible of 70% of cervical cancers worldwide. HIV infection is...
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Analysis of the immune-inflammatory indices for patients with metastatic hormone-sensitive and castration-resistant prostate cancer
BackgroundInflammation plays a pivotal role in the progression of prostate cancer (PCa). Several immune-inflammatory indices, including neutrophil to...
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Novel associations between MTDH gene polymorphisms and invasive ductal breast cancer: a case–control study
ObjectiveTo reveal the contributing effects of MTDH gene SNPs in the risk of invasive ductal breast cancer (IDC).
Patients and methods ... -
Evidence-based clinical practice guidelines for the management of acute ankle injuries according to: a PRISMA systematic review and quality appraisal with AGREE II
BackgroundAcute ankle injuries are commonly seen in emergency rooms, with significant social impact and potentially devastating consequences. While...
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Stromal lymphocytes are associated with upgrade of B3 breast lesions
Various histopathological, clinical and imaging parameters have been evaluated to identify a subset of women diagnosed with lesions with uncertain...
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Effects of the subtypes of apolipoprotein E on immune inhibition and prognosis in patients with Hepatocellular Carcinoma
PurposeTo investigate whether prognosis of patients with hepatocellular carcinoma (HCC) is affected by the abundance and subgroups of myeloid-derived...
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FERMT1 suppression induces anti-tumor effects and reduces stemness in glioma cancer cells
ObjectiveGlioma is a leading cause of mortality worldwide, its recurrence poses a major challenge in achieving effective treatment outcomes. Cancer...
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Similar genetic profile in early and late stage urothelial tract cancer
IntroductionUrothelial tract cancer (UTC) ranks as the tenth most prevalent cancer and holds the seventh position in terms of mortality worldwide....
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Health outcomes and healthcare utilization associated with four undiagnosed chronic conditions: evidence from nationally representative survey data in Sri Lanka
BackgroundLow awareness of chronic conditions raises the risk of poorer health outcomes and may result in healthcare utilization and spending in...
