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The SHOW RESPECT adaptable framework of considerations for planning how to share trial results with participants, based on qualitative findings from trial participants and site staff
BackgroundSharing trial results with participants is a moral imperative, but too often does not happen in appropriate ways.
MethodsWe carried out...
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Effect of modified Baduan** exercise on nutritional status in patients with nasopharyngeal carcinoma: a randomized controlled trial
BackgroundAs a traditional Chinese fitness technique, Baduan** is a low- to medium-intensity aerobic exercise that has a common regulatory effect on...
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Assessment of the American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS™) with modification of the management recommendations for pediatric thyroid nodules
BackgroundThyroid nodules are unusual in children, but when present, they carry a higher risk for malignancy, as compared to adults. Several...
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A small molecule compound targeting hemagglutinin inhibits influenza A virus and exhibits broad-spectrum antiviral activity
Influenza A virus (IAV) is a widespread pathogen that poses a significant threat to human health, causing pandemics with high mortality and...
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Breaking the silence: the role of sexual communication on quality of life in women with cervical cancer
IntroductionCervical cancer (CC) and its treatments impact various dimensions of quality of life (QoL), including physical, psychological, and sexual...
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A Comprehensive on Synthesis and Antimicrobial Evaluation of Substituted-Arylideneamino-5-(5-Chlorobenzofuran-2-yl)-1, 2, 4-Triazole-3-Thiol Derivatives/ Schiff Bases
Schiff bases are well known and popular classes of organic compounds containing imine (R 2 C = NH) group that are widely used as catalysts and...
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The black box of the relationship between breast cancer patients and accompanying patients: the accompanied patients’ point of view
BackgroundThe PAROLE-Onco program was introduced in the province of Quebec, Canada in 2019. It integrates accompanying patients (APs), i.e., people...
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“Not me!” a qualitative, vignette-based study of nurses’ and physicians’ reactions to spiritual distress on neuro-oncological units
PurposePeople with primary malignant brain tumors experience serious health-related suffering caused by limited prognosis and high symptom burden....
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Operative Therapie des Vulva- und Vaginalkarzinoms
Surgical treatment of cancer of the vulva and vagina is an important part of therapy. Complete removal of the tumour with an adequate safety margin...
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Goat weed (Ageratum conyzoides L.): A biological threat to plant diversity in Eastern Ghats of India
The Kunming–Montreal Global Biodiversity Framework (GBF) is a recently signed protocol by the conference of the parties (COP 15) with an aim to...
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High-sensitivity whole-mount in situ Hybridization of Mouse Oocytes and Embryos Visualizes the Super-resolution Structures and Distributions of mRNA Molecules
Mammalian oocytes accumulate more than ten thousand mRNAs, of which three to four thousand mRNAs are translationally repressed. The timings and sites...
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Systematic optimization of prime editing for the efficient functional correction of CFTR F508del in human airway epithelial cells
Prime editing (PE) enables precise and versatile genome editing without requiring double-stranded DNA breaks. Here we describe the systematic...
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Strategies for modeling aging and age-related diseases
The ability to reprogram patient-derived-somatic cells to IPSCs (Induced Pluripotent Stem Cells) has led to a better understanding of aging and...
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Transperineal laser ablation (TPLA) of the prostate for benign prostatic obstruction: the first 100 patients cohort of a prospective, single-center study
PurposeTransperineal laser ablation (TPLA) is a new minimally-invasive surgical treatment for patients with benign prostatic obstruction (BPO). We...
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Bone Turnover Markers Levels in a Cohort of Egyptian Children with Sickle Cell Disease
Bony complications are variable and common in sickle cell disease. Bone turnover markers are a reflection of bone new bone formation or degradation....
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Machine learning enables automated screening for systematic reviews and meta-analysis in urology
PurposeTo investigate and implement semiautomated screening for meta-analyses (MA) in urology under consideration of class imbalance.
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