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1. Characterization of 13 Novel Genetic Variants in Genes Associated with Epilepsy: Implications for Targeted Therapeutic Strategies

   Background

   Childhood epilepsies are caused by heterogeneous underlying disorders where approximately 40% of the origins of epilepsy can be attributed...

   Marina Andjelkovic, Kristel Klaassen, ... Maja Stojiljkovic in Molecular Diagnosis & Therapy

   Article Open access 14 July 2024
   

2. Loss of sheen in Oguchi disease following short wavelength exposure

   Haseeb N. Akhtar, Luke Nicholson, ... Omar A. Mahroo in Eye

   Article Open access 14 July 2024
   

3. Potential therapeutic effects of ester derivatives of Ribavirin against SARS-CoV-2

   Ribavirin ( 1 ) esters 4–36 have been synthesized and tested for their anti-inflammatory and anti-viral properties against SARS-CoV-2. The impaired...

   Aaminat Qureshi, Samina Bano in Medicinal Chemistry Research

   Article 14 July 2024
   

4. A versatile functional interaction between electrically silent K_V subunits and K_V7 potassium channels

   Voltage-gated K ⁺ (K _V ) channels govern K ⁺ ion flux across cell membranes in response to changes in membrane potential. They are formed by the assembly...

   Vijay Renigunta, Nermina Xhaferri, ... Moritz Lindner in Cellular and Molecular Life Sciences

   Article Open access 14 July 2024
   

5. Effects of Commonly used Surfactants, Poloxamer 188 and Tween 80, on the Drug Transport Capacity of Intestinal Glucose Transporters

   Some glycoside drugs can be transported through intestinal glucose transporters (IGTs). The surfactants used in oral drug preparations can affect the...

   Jiasheng Chen, Zhenzhen Chen, ... Zheng Cai in AAPS PharmSciTech

   Article 13 July 2024
   

6. Dietary salt promotes cognitive impairment through repression of SIRT3/PINK1-mediated mitophagy and fission

   Dietary salt is increasingly recognized as an independent risk factor for cognitive impairment. However, the exact mechanisms are not yet fully...

   Haixia Fan, Minghao Yuan, ... Zhiyou Cai in Molecular and Cellular Biochemistry

   Article 13 July 2024
   

7. Physiological and cellular mechanisms of ischemic preconditioning microRNAs-mediated in underlying of ischemia/reperfusion injury in different organs

   Ischemia–reperfusion (I/R) injury, as a pathological phenomenon, takes place when blood supply to an organ is disrupted and then aggravated during...

   Izadpanah Gheitasi, Ghaidafeh Akbari, Feryal Savari in Molecular and Cellular Biochemistry

   Article 13 July 2024
   

8. Preclinical and clinical advances to overcome hypoxia in glioblastoma multiforme

   Glioblastoma multiforme (GBM) is the most common adult primary brain tumor. The standard clinical treatment of GBM includes a maximal surgical...

   Jolie Bou-Gharios, Georges Noël, Hélène Burckel in Cell Death & Disease

   Article Open access 13 July 2024
   

9. Safety and Efficacy of Covered Self-Expandable Metallic Stent for Choledochojejunal Anastomotic Stricture: A Multi-Center Retrospective Cohort Study

   Background

   Benign choledochojejunal anastomotic stricture (CJS) is a complication of pancreaticoduodenectomy and choledochojejunostomy. Typically...

   Yuhei Iwasa, Takuji Iwashita, ... Masahito Shimizu in Digestive Diseases and Sciences

   Article 13 July 2024
   

10. Synthetic Alfalfa Infusion Odour Attracts Gravid Culex quinquefasciatus Under Laboratory Conditions

    Gravid culicine mosquitoes rely on olfactory cues for selecting breeding sites containing organic detritus. While this capacity of the mosquitoes is...

    Betelehem Wondwosen, Elin Isberg, ... Rickard Ignell in Journal of Chemical Ecology

    Article Open access 13 July 2024
    

11. Pipette-tip solid-phase extraction coupled with matrix-assisted laser desorption/ionization mass spectrometry enables rapid and high-throughput analysis of antidepressants in rat serum

    Therapeutic drug monitoring is essential for ensuring the efficacy and safety of medications. This study introduces a streamlined approach that...

    Zhi Sun, Fangfang Wang, ... Lihua Zuo in Analytical and Bioanalytical Chemistry

    Article 13 July 2024
    

12. Polyploidy in maize: from evolution to breeding

    Polyploidy played an important role in the evolution of the three most important crops: wheat, maize and rice, each of them providing a unique model...

    Grigorii Batiru, Thomas Lübberstedt in Theoretical and Applied Genetics

    Article 13 July 2024

13. Age-related dysregulation of CXCL9/10 in monocytes is linked to impaired innate immune responses in a mouse model of Staphylococcus aureus osteomyelitis

    Background

    Age-associated impairments in innate immunity are believed to be a causative factor responsible for severe pathogenesis of Staphylococcus...

    Yihuang Lin, Mankai Yang, ... **anrong Zhang in Cellular and Molecular Life Sciences

    Article Open access 13 July 2024
    

14. Unveiling the Role of Angiosperm Pollen Morphology in Attachment to the Moth (Lepidoptera) Proboscides

    Abstract

    The current study aims to understand the role of various morphological features of pollen grains in attachment with moth proboscides. To test...

    Dipayan Mitra, Rajesh Lenka, ... Navneet Singh in Biology Bulletin

    Article 13 July 2024
    

15. Identification of Tissue Expression Characteristics of Pig ALKBH5 and Its Association with Pathogenic Microbial Infection

    Abstract

    N ⁶ -methyladenosine (m ⁶ A) as a reversible RNA modification has become a new direction and hotspot of RNA epigenetics research in the field of...

    Yuan Bian, Yifan Xu, ... Zhengchang Wu in Biology Bulletin

    Article 13 July 2024
    

16. GC × GC-HRMS with complementary ionization methods in the suspect screening analysis of fragrance allergens: overwhelming or justified?

    Modern gas chromatography-mass spectrometry (GC–MS) allows for the analysis of complex samples, such as fragrances. However, identifying all the...

    Dmitrii M. Mazur, Vyacheslav B. Artaev, Albert T. Lebedev in Analytical and Bioanalytical Chemistry

    Article 13 July 2024
    

17. Anti-Carbamylated Protein Antibodies in ACPA-Negative and ACPA-Positive Patients with Rheumatoid Arthritis

    Abstract

    The objective of this study was to assess the level of antibodies to carbamylated proteins and analyze the clinical and immunological...

    D. A. Dibrov, A. S. Avdeeva, ... E. L. Nasonov in Doklady Biochemistry and Biophysics

    Article 13 July 2024
    

18. Sexual Size Dimorphism in Buthus tunetanus (Scorpiones: Buthidae) from Tunisia

    Abstract

    Scorpions are known to exhibit sexual size dimorphism, but data is still lacking from a large number of species throughout the world. Such...

    Sarra Hajri, Jamel Babay, ... Saïd Nouira in Biology Bulletin

    Article 13 July 2024
    

19. Clinical Features of ACPA-Negative and ACPA-Positive Variants of Rheumatoid Arthritis

    Abstract

    The aim of the study was to investigate the features of the clinical picture of the disease in patients with ACPA–negative and ACPA-positive...

    D. A. Dibrov, A. S. Avdeeva, ... E. L. Nasonov in Doklady Biochemistry and Biophysics

    Article 13 July 2024
    

20. Growth Characteristics of 10 Deep-Sea Demersal Scorpaenoid Fish Species from the Arabian Sea: Insights for Database Update and Fisheries Management

    Abstract

    The present study provides length-weight relationships (LWRs) and condition factors (Kn) estimates for ten deep-sea scorpaeniform fishes...

    D. Nihal, K. V. Aneesh Kumar, ... H. Manjebrayakath in Biology Bulletin

    Article 13 July 2024