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  1. Effect of sagittal alignment on spinal cord biomechanics in the stenotic cervical spine during neck flexion and extension

    Spinal cord stress and strain contribute to degenerative cervical myelopathy (DCM), while cervical kyphosis is known to negatively impact surgical...

    Shalini Gundamraj, Karthik Banurekha Devaraj, ... Aditya Vedantam in Biomechanics and Modeling in Mechanobiology
    Article 14 July 2024
  2. Measuring and Understanding Market Exclusivity Length for New Prescription Drugs in France, Australia, and the USA

    Background

    Originator drug manufacturers use several strategies to delay generic competition in the USA, but it remains unclear whether this results...

    Victor L. Van de Wiele, Aaron S. Kesselheim, ... Benjamin N. Rome in Pharmaceutical Medicine
    Article 14 July 2024
  3. Potential therapeutic effects of ester derivatives of Ribavirin against SARS-CoV-2

    Ribavirin ( 1 ) esters 4–36 have been synthesized and tested for their anti-inflammatory and anti-viral properties against SARS-CoV-2. The impaired...

    Aaminat Qureshi, Samina Bano in Medicinal Chemistry Research
    Article 14 July 2024
  4. A versatile functional interaction between electrically silent KV subunits and KV7 potassium channels

    Voltage-gated K + (K V ) channels govern K + ion flux across cell membranes in response to changes in membrane potential. They are formed by the assembly...

    Vijay Renigunta, Nermina Xhaferri, ... Moritz Lindner in Cellular and Molecular Life Sciences
    Article Open access 14 July 2024
  5. Effects of Commonly used Surfactants, Poloxamer 188 and Tween 80, on the Drug Transport Capacity of Intestinal Glucose Transporters

    Some glycoside drugs can be transported through intestinal glucose transporters (IGTs). The surfactants used in oral drug preparations can affect the...

    Jiasheng Chen, Zhenzhen Chen, ... Zheng Cai in AAPS PharmSciTech
    Article 13 July 2024
  6. Dietary salt promotes cognitive impairment through repression of SIRT3/PINK1-mediated mitophagy and fission

    Dietary salt is increasingly recognized as an independent risk factor for cognitive impairment. However, the exact mechanisms are not yet fully...

    Haixia Fan, Minghao Yuan, ... Zhiyou Cai in Molecular and Cellular Biochemistry
    Article 13 July 2024
  7. Analysis of Oncology and Radiation Therapy Representation on the National Board of Medical Examiners Official Practice Material for the United States National Standardized Medical Board Examinations

    Radiation therapy (RT) is a critical component of multidisciplinary cancer care, but has inconsistent curricular exposure. We characterize the...

    Mary T. Mahoney, Lauren C. Linkowski, ... Malcolm D. Mattes in Journal of Cancer Education
    Article Open access 13 July 2024
  8. Platelet-Rich Plasma Promotes the Expansion of Human Myoblasts and Favors the In Vitro Generation of Human Muscle Reserve Cells in a Deeper State of Quiescence

    Stem cell therapy holds significant potential for skeletal muscle repair, with in vitro-generated human muscle reserve cells (MuRCs) emerging as a...

    Axel Tollance, Alexandre Prola, ... Thomas Laumonier in Stem Cell Reviews and Reports
    Article Open access 13 July 2024
  9. Methylprednisolone

    Article 13 July 2024
  10. Immunosuppressants

    Article 13 July 2024
  11. Prednisolone

    Article 13 July 2024
  12. Pembrolizumab

    Article 13 July 2024
  13. Meropenem

    Article 13 July 2024
  14. Heparin

    Article 13 July 2024
  15. Methotrexate

    Article 13 July 2024
  16. Minocycline

    Article 13 July 2024
  17. Mirtazapine

    Article 13 July 2024
  18. Marijuana

    Article 13 July 2024
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