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Breast cancer preventive practices and associated factors among reproductive age women in Wadila District, North East Ethiopia: community based cross-sectional study
BackgroundCancer is one of the leading causes of morbidity and mortality worldwide. Among all cancer types, breast cancer stands out as the most...
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A multidisciplinary group-based survivorship intervention for those living with multiple myeloma: a feasibility study
BackgroundWhile multiple myeloma continues to be an incurable cancer, advances in its understanding and management have led to significantly improved...
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Facile biotic/abiotic sandwich detection system for the highly sensitive detection of human serum albumin and glycated albumin
Quantifying glycated albumin (GA) levels in the blood is crucial for diagnosing diabetes because they strongly correlate with blood glucose...
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Inexpensive and colorimetric RNA detection at ambient temperature with a cell-free protein synthesis platform
While many proposals of paper-based diagnostics utilize cell-free gene expression systems, these assays oftentimes suffer from the need for...
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Lessons from the physiological role of guanosine in neurodegeneration and cancer: Toward a multimodal mechanism of action?
Neurodegenerative diseases and brain tumours represent important health challenges due to their severe nature and debilitating consequences that...
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Effects of high-intensity interval training on cardiometabolic biomarkers in patients with prostate cancer undergoing active surveillance: a randomized controlled trial
PurposeTo report the effects of a 12-week high-intensity interval training (HIIT) program on cardiometabolic biomarkers in patients with prostate...
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Nonadherence to oral cancer chemotherapy in hepatocellular carcinoma: prevalence and predictive factors in Vietnam
PurposeStandard oral cancer chemotherapy (OCT) or targeted therapy (OTT) has expanded the treatment methods for hepatocellular carcinoma (HCC)....
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A Ratiometric Benzimidazole-Based Fluorescent Probe for The Recognition of Phosgene in Solution and Gaseous Phases
Considering the high toxicity and widespread application of phosgene, there is an urgent need to develop a simple and sensitive method for detecting...
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A novel class of indole derivatives: enhanced bioavailability, permeability, and antioxidant efficacy for thromboembolic disease therapy
Free radicals like reactive oxygen species (ROS) and reactive nitrogen species (RNS) cause cellular damage and contribute to thromboembolic diseases...
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Role of Low-Voltage Electrostatic Field-Vacuum in Delaying Postharvest Senescence of White Hypsizygus marmoreus
Membrane lipid peroxidation and cell wall component degradation can accelerate the aging process of fresh mushroom. Fresh mushroom confronted with...
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DAP12 interacts with RER1 and is retained in the secretory pathway before assembly with TREM2
DNAX-activating protein of 12 kDa (DAP12) is a transmembrane adapter protein expressed in lymphoid and myeloid lineage cells. It interacts with...
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TOTEM: a multi-cancer detection and localization approach using circulating tumor DNA methylation markers
BackgroundDetection of cancer and identification of tumor origin at an early stage improve the survival and prognosis of patients. Herein, we...
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A flexible glucose biosensor modified by reduced-swelling and conductive zwitterionic hydrogel enzyme membrane
This paper reports a flexible glucose biosensor which is modified by a reduced-swelling and conductive zwitterionic hydrogel enzyme membrane that...
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Targeting oncogene-induced cellular plasticity for tumor therapy
Cellular plasticity, the remarkable adaptability of cancer cells to survive under various stress conditions, is a fundamental hallmark that...
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Controllable self-cleaning FET self-assembled RNA-cleaving DNAzyme based DNA nanotree for culture-free Staphylococcus aureus detection
Staphylococcus aureus (SA) poses a serious risk to human and animal health, necessitating a low-cost and high-performance analytical platform for...
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SNCA is a potential therapeutic target for COVID-19 infection in diffuse large B-cell lymphoma patients
Cuprotosis related genes (CRGs) have been proved to be potential therapeutic targets for coronavirus disease 2019 (COVID-19) and cancer, but their...
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Enteroviruses: epidemic potential, challenges and opportunities with vaccines
Enteroviruses (EVs) are the most prevalent viruses in humans. EVs can cause a range of acute symptoms, from mild common colds to severe systemic...
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Heterotrimeric collagen helix with high specificity of assembly results in a rapid rate of folding
The most abundant natural collagens form heterotrimeric triple helices. Synthetic mimics of collagen heterotrimers have been found to fold slowly,...
