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  1. Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition

    SF3B1 mutations frequently occur in cancer yet lack targeted therapies. Clinical trials of XPO1 inhibitors, selinexor and eltanexor, in high-risk...

    Sana Chaudhry, Felipe Beckedorff, ... Justin Taylor in Leukemia
    Article Open access 13 July 2024

  2. PET imaging of neuroinflammation: any credible alternatives to TSPO yet?

    Over the last decades, the role of neuroinflammation in neuropsychiatric conditions has attracted an exponentially growing interest. A key driver for...

    Fabien Chauveau, Alexandra Winkeler, ... Guillaume Becker in Molecular Psychiatry
    Article 13 July 2024

  3. Doing a double take: when transthoracic echocardiography fails for mitral valve annuloplasty ring endocarditis with Streptococcus pyogenes: a case report

    Background

    This case highlights several complications of a late and rare presentation of culture-negative Streptococcus pyogenes endocarditis of a...

    Jonathan K. Schilling, Robert Tungate, ... Antonio H. Frangieh in Journal of Medical Case Reports
    Article Open access 13 July 2024

  4. Death anxiety among caregivers of patients with advanced cancer: a cross-sectional survey

    Purpose

    This study aimed to investigate death anxiety (DA) in caregivers of patients with advanced cancer and identify associated factors in the...

    Li Ying, Duan Yuyu, ... Zhou Zhihuan in Supportive Care in Cancer
    Article 13 July 2024

  5. Safety and Efficacy of Covered Self-Expandable Metallic Stent for Choledochojejunal Anastomotic Stricture: A Multi-Center Retrospective Cohort Study

    Background

    Benign choledochojejunal anastomotic stricture (CJS) is a complication of pancreaticoduodenectomy and choledochojejunostomy. Typically...

    Yuhei Iwasa, Takuji Iwashita, ... Masahito Shimizu in Digestive Diseases and Sciences
    Article 13 July 2024

  6. Deep learning model based on endoscopic images predicting treatment response in locally advanced rectal cancer undergo neoadjuvant chemoradiotherapy: a multicenter study

    Purpose

    Neoadjuvant chemoradiotherapy has been the standard practice for patients with locally advanced rectal cancer. However, the treatment response...

    Junhao Zhang, Ruiqing Liu, ... Yun Lu in Journal of Cancer Research and Clinical Oncology
    Article Open access 13 July 2024

  7. Assessing risk for severe domestic violence and related homicides perpetrated by partners and in-laws: adapted danger assessments for women in abusive relationships in India

    Despite domestic violence and related homicides perpetrated by partners and/or in-laws being a significant public health problem in India, there are...

    Bushra Sabri, Jacquelyn C. Campbell, ... Mohd Naseem Khan in BMC Public Health
    Article Open access 13 July 2024

  8. Relationship between the severity of functional mitral regurgitation at admission and one-year outcomes in patients hospitalized for acute heart failure with mildly reduced ejection fraction

    Background

    The epidemiological distribution of functional mitral regurgitation (FMR) in heart failure (HF) and mildly reduced ejection fraction...

    Zhenhua Wang, Yue Zeng, ... Chaosheng Li in BMC Cardiovascular Disorders
    Article Open access 13 July 2024

  9. Neuroprotective and vasoprotective effects of herb pair of Zhiqiao-Danggui in ischemic stroke uncovered by LC-MS/MS-based metabolomics approach

    Ischemic stroke is the most important cause of disability and death worldwide, but current treatments remain limited. Traditional Chinese medicine...

    Benxing Yao, Di Xu, ... Junsong Wang in Metabolic Brain Disease
    Article 13 July 2024

  10. Buprenorphine vs. morphine: impact on neonatal opioid withdrawal syndrome (NOWS) outcomes in a single center retrospective study

    Objectives

    To compare clinical outcomes for infants with neonatal opioid withdrawal syndrome (NOWS) treated with buprenorphine or morphine.

    ...
    Saminathan Anbalagan, Victoria Anderson, ... Zubair H. Aghai in Journal of Perinatology
    Article Open access 13 July 2024

  11. A bipolar disorder-associated missense variant alters adenylyl cyclase 2 activity and promotes mania-like behavior

    The single nucleotide polymorphism rs13166360, causing a substitution of valine (Val) 147 to leucine (Leu) in the adenylyl cyclase 2 (ADCY2), has...

    Paromita Sen, Oskar Ortiz, ... Jan M. Deussing in Molecular Psychiatry
    Article Open access 13 July 2024

  12. Experimental study on the safety of photobiologic regulation therapy in the treatment of some non-epidermal tumors

    This study investigates the impact of Photobiomodulation (PBM) at different wavelengths on non-superficial cancer cells. Utilizing three laser...

    Fang Nie, Yu Ji, ... YuChuan Ding in Lasers in Medical Science
    Article 13 July 2024

  13. Carbon-ion radiotherapy alone vs. standard dose photon radiation with carbon-ion radiotherapy boost for high-grade gliomas: a retrospective study

    Background

    This study aimed to compare the survival outcome and side effects in patients with primary high-grade glioma (HGG) who received carbon ion...

    **aoJun Li, YanShan Zhang, ... Faxin Wen in BMC Cancer
    Article Open access 13 July 2024

  14. Hyponatremia Is Associated with Mortality in Acute Pancreatitis Patients

    Background

    Disorders of serum sodium are common among general patients and are associated with poor outcomes. The prognostic value of serum sodium...

    Liqing Song, Wen Tang, ... Ying Xu in Digestive Diseases and Sciences
    Article 13 July 2024

  16. Statins for the Primary Prevention of Anthracycline Cardiotoxicity: A Comprehensive Review

    Purpose of Review

    The aim of this review is two-fold: (1) To examine the mechanisms by which statins may protect from anthracycline-induced...

    Varun Bhasin, Azin Vakilpour, Marielle Scherrer-Crosbie in Current Oncology Reports
    Article Open access 13 July 2024

  17. Multiple lung abscesses and cold agglutinin syndrome following coronavirus disease 2019: a case report

    Background

    Cold agglutination syndrome is a subtype of autoimmune hemolytic anemia. The condition is referred to as “cold” because the antibodies...

    Masaharu Aga, So Okubo, ... Hiroaki Okamoto in Journal of Medical Case Reports
    Article Open access 13 July 2024

  18. Reducing racial and ethnic disparities in cardiovascular outcomes among cancer survivors

    Purpose of review

    Analyze current evidence on racial/ethnic disparities in cardiovascular outcomes among cancer survivors, identifying factors and...

    Min Choon Tan, Nickolas Stabellini, ... Avirup Guha in Current Oncology Reports
    Article 13 July 2024

  20. Voices Unheard: Navigating the Disempowerment of Older Adults in Family Dynamics in Kashmir (India)

    This paper attempts to investigate the dwindling status of older adults within family settings in Kashmir, specifically focusing on their...

    Amir Mohammad Wani, Aneesa Shafi, Mohmad Saleem Jahangir in Journal of Population Ageing
    Article 13 July 2024
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