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Safety and Psychological Outcomes of Tandem t:Slim X2 Insulin Pump with Control-IQ Technology in Children, Adolescents, and Young Adults with Type 1 Diabetes: A Systematic Review
The Tandem t:slim X2 insulin pump is a second-generation automated insulin delivery system with Control-IQ technology. It consists of an X2 insulin...
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Tirzepatide Improved Health-Related Quality of Life Compared with Insulin Lispro in Basal Insulin-Treated Adults with Type 2 Diabetes and Inadequate Glycaemic Control: A Randomised Controlled Phase 3b Trial (SURPASS-6)
IntroductionPatients with type 2 diabetes (T2D) who require intensification of basal insulin therapy need treatment options that can improve their...
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Association of Changes in A1C Following Continuous Glucose Monitoring Acquisition in People with Sub-Optimally Treated Type 2 Diabetes Taking GLP-1 RA Therapy
IntroductionBoth glucagon-like peptide-1 receptor agonists (GLP-1 RA) and continuous glucose monitoring (CGM) improve glycemia in patients with type...
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Orale Antikoagulation bei supraventrikulären Rhythmusstörungen
Atrial fibrillation represents the most frequent persistent cardiac arrhythmia and is associated with an increased morbidity and mortality. An...
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Prompt closure versus gradual weaning of external ventricular drain for hydrocephalus following aneurysmal subarachnoid haemorrhage: a statistical analysis plan for the DRAIN randomised clinical trial
BackgroundInsertion of an external ventricular drain (EVD) is a first-line treatment of acute hydrocephalus caused by aneurysmal subarachnoid...
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Vorhofflimmern und Herzinsuffizienz
Atrial fibrillation and heart failure are among the most common cardiovascular diseases and have a significant impact on the mortality and morbidity...
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Tumoral periprostatic adipose tissue exovesicles-derived miR-20a-5p regulates prostate cancer cell proliferation and inflammation through the RORA gene
BackgroundFrom the first steps of prostate cancer (PCa) initiation, tumours are in contact with the most-proximal adipose tissue called periprostatic...
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Theory of change for addressing sex and gender bias, invisibility and exclusion in Australian health and medical research, policy and practice
Sex and gender are inadequately considered in health and medical research, policy and practice, leading to preventable disparities in health and...
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A protocol for the formative evaluation of the implementation of patient-reported outcome measures in child and adolescent mental health services as part of a learning health system
BackgroundMental health conditions affect one in seven young people and research suggests that current mental health services are not meeting the...
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Obstructive Sleep Apnea and Short-Term Outcomes After Pediatric Cardiac Surgery
Obstructive sleep apnea (OSA) has been associated with negative cardiovascular effects and negative outcomes following cardiovascular surgery in the...
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The challenges of assessing adiposity in a clinical setting
To tackle the burden of obesity-induced cardiometabolic disease, the scientific community relies on accurate and reproducible adiposity measurements...
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Safety and feasibility of pulmonary vein isolation utilizing pulsed field ablation in patients with symptomatic atrial fibrillation and implanted Watchman devices
BackgroundPulsed field ablation (PFA) is a novel method of non-thermal cardiac ablation for atrial fibrillation (AF). Its use on patients with...
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Prenatal affective cognitive training to reduce the risk of postpartum depression (PACT): study protocol for a randomized controlled trial
BackgroundPostpartum depression (PPD) affects 30–50% of women with a history of previous depression or bipolar disorder and 8% of women with no...
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Perception of couples’ on multipurpose prevention technology attribute choice: the case of MTN 045
BackgroundMultipurpose prevention technologies (MPTs) are products capable of simultaneously addressing multiple sexual and reproductive health needs...
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Risk factors for persistent fatal opioid-involved overdose clusters in Massachusetts 2011–2021: a spatial statistical analysis with socio-economic, accessibility, and prescription factors
BackgroundFatal opioid-involved overdose rates increased precipitously from 5.0 per 100,000 population to 33.5 in Massachusetts between 1999 and 2022.
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Short-term S100A8/A9 Blockade Promotes Cardiac Neovascularization after Myocardial Infarction
Acute-phase inhibition of the pro-inflammatory alarmin S100A8/A9 improves cardiac function post-myocardial infarction (MI), but the mechanisms...
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Fontan Circulation and Aortic Stiffness: Insights into Vascular Dynamics and Haemodynamic Interplay
AbstractIncreased aortic stiffness predisposes cardiac afterload and influences cardiac function. Congenital heart diseases involving aortic arch...
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Global prevalence and predictors of scabies among prisoners: systematic review and meta-analysis
IntroductionScabies is a widespread issue in prisons due to overcrowded living conditions and limited healthcare resources. A recent study published...
