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Lessons from the physiological role of guanosine in neurodegeneration and cancer: Toward a multimodal mechanism of action?
Neurodegenerative diseases and brain tumours represent important health challenges due to their severe nature and debilitating consequences that...
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A simple projection method to correlate the principal mechanical direction with the principal microstructural direction of human osteoporotic femoral heads
The mechanics of the trabecular bone is related to its structure; this work aimed to propose a simple projection method to clarify the correlation...
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Sex-specific role of high-fat diet and stress on behavior, energy metabolism, and the ventromedial hypothalamus
BackgroundScientific evidence highlights the influence of biological sex on the relationship between stress and metabolic dysfunctions. However,...
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A Short Game-Based Intervention for Enhancing Executive Functions at School: a Pilot Study
Executive functions (EFs) are crucial for self-regulation, and they can explain the difficulties that many children face at school in terms of both...
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Stability of N-type inactivation and the coupling between N-type and C-type inactivation in the Aplysia Kv1 channel
The voltage-dependent potassium channels (Kv channels) show several different types of inactivation. N-type inactivation is a fast inactivating...
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The developmental phenotype of motor delay in extremely preterm infants following early-life respiratory adversity is influenced by brain dysmaturation in the parietal lobe
BackgroundResearch indicates that preterm infants requiring prolonged mechanical ventilation often exhibit suboptimal neurodevelopment at follow-up,...
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Measurement of left ventricular volume with admittance incorporated onto percutaneous ventricular assist device
Percutaneous ventricular assist devices (pVADs) incorporated with admittance electrodes have been validated in animal studies for accurate...
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Estimating the Trial-by-Trial Learning Curve in Perceptual Learning with Hierarchical Bayesian Modeling
The learning curve serves as a crucial metric for assessing human performance in perceptual learning. It may encompass various component processes,...
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Evaluation of postoperative results after a presurgical optimisation programme
BackgroundPresurgical optimisation programmes decrease the risk of postoperative complications, reduce hospital stays and speed up patient recovery....
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Ile-Pro-Pro attenuates sympathetic activity and hypertension
Isoleucine-proline-proline (Ile-Pro-Pro, IPP) is a natural food source tripeptide that inhibits angiotensin-converting enzyme (ACE) activity. The aim...
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The infrapatellar fat pad in inflammaging, knee joint health, and osteoarthritis
Osteoarthritis (OA) is the most common form of arthritis and accounts for nearly $140 billion in annual healthcare expenditures only in the United...
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Effects of exercise mimetics as putative therapeutics on brain health, aging, and neurodegenerative diseases
There is growing evidence that an active lifestyle can benefit brain health, delay the onset of neurodegenerative diseases and aging, and improve...
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Ultra-processed food consumption and risk of diabetes: results from a population-based prospective cohort
Aims/hypothesisUnderstanding the impact of the overall construct of ultra-processed foods on diabetes risk can inform dietary approaches to diabetes...
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The relationship between the functional movement screen and isokinetic muscle strength around the knee in different sports
The aim of this study was to determine objective data of the relationship between the Functional Movement Screen (FMS) and isokinetic muscle strength...
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A scarce combination of arterial variants: an occipital artery originating from the internal carotid artery associated with a linguofacial trunk
The occipital artery (OA) typically originates from the external carotid artery (ECA). Variations of the ECA has been well described in the current...
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An evaluation of morphometry and dehiscence of facial canal: a systematic review and meta-analysis of observational studies
IntroductionThe facial canal (FC) is an extensive bony canal that houses the facial nerve and occupies a central position in the petrous part of...
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Sex differences in membrane properties and cellular excitability of dopamine D1 receptor-expressing neurons within the shell of the nucleus accumbens of pre- and mid-adolescent mice
BackgroundThe transition from childhood to adulthood, or adolescence, a developmental stage, is characterized by psychosocial and biological changes....
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Bedside electromyography for clinical assessment of sacral motor and reflex activity adapted for patients hospitalized with acute neurological conditions: a pilot study
Study designPilot cohort study.
ObjectiveTo develop and implement a sacral electromyographic (sEMG) technique at bedside to ascertain sparing of...
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Use of diabetes technology in children
Children with type 1 diabetes and their caregivers face numerous challenges navigating the unpredictability of this complex disease. Although the...
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Multimodal training protocols on unstable rather than stable surfaces better improve dynamic balance ability in older adults
BackgroundThere has been growing interest in using unstable devices in training protocols. This study aimed to assess the effectiveness of two...
