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Lower or higher oxygenation targets in the intensive care unit: an individual patient data meta-analysis
PurposeOptimal oxygenation targets for patients with acute hypoxemic respiratory failure in the intensive care unit (ICU) are not clearly defined due...
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The Effect of Long-Term Azithromycin on Objective and Subjective Cough in Chronic Respiratory Disease: A Systematic Review and Meta-analysis of Randomised Controlled Trials and Noncomparative Studies
IntroductionAzithromycin is an effective treatment for various respiratory conditions but its effect on cough is poorly understood. We synthesised...
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Childhood asthma and mould in homes—A meta-analysis
Asthma is a multifaceted and multicausal disease. Childhood asthma is strongly influenced by genetic traits and is characterized by hyperreactivity...
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Physiologic and anatomic determinants of hyoid motion during drug-induced sleep endoscopy
PurposeTo examine factors accounting for differences in hyoid motion during obstructive breathing events amongst obstructive sleep apnea (OSA)...
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Tezepelumab for refractory eosinophilic granulomatosis with polyangiitis-related asthma
Conventional immunosuppressants are ineffective for the management of EGPA-related asthma. Tezepelumab is a human monoclonal antibody that inhibits...
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Burden of illness in patients with pulmonary hypertension due to interstitial lung disease: a real-world analysis
BackgroundPulmonary hypertension due to interstitial lung disease (PH-ILD) is associated with high rates of respiratory failure and death. Healthcare...
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A retrospective analysis of treatment patterns, overall survival, and real-world disease-free survival in early-stage non-small cell lung cancer following complete resection
BackgroundReal-world data regarding patient characteristics, adjuvant treatment patterns, and long-term survival outcomes are needed to better...
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Assessment of the importance of sleep quality and the effects of deprivation on Sudanese healthcare professionals amidst conflict in Sudan
BackgroundQuality sleep is vital for well-being, especially for healthcare workers facing high risks of fatigue and burnout. Sleep deprivation...
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Esophageal perforation with near fatal mediastinitis secondary to Th3 fracture
A 74-year-old male patient was referred with signs of sepsis 5 days after having been diagnosed with a rib fracture following a fall out of bed....
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LncRNAH19 acts as a ceRNA of let-7 g to facilitate endothelial-to-mesenchymal transition in hypoxic pulmonary hypertension via regulating TGF-β signalling pathway
BackgroundHypoxic pulmonary hypertension (HPH) is a challenging lung arterial disorder with remarkably high incidence and mortality rates, and the...
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Analysis of the impact of a university distance learning course on digitalization in medicine on students and healthcare professionals
PurposeThe public medical universities in Austria (educating 11,000 students) developed a joint public distance learning series in which clinicians...
