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Measuring and Understanding Market Exclusivity Length for New Prescription Drugs in France, Australia, and the USA
BackgroundOriginator drug manufacturers use several strategies to delay generic competition in the USA, but it remains unclear whether this results...
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Efficacy and safety of topical azithromycin therapy in patients with blepharitis and meibomian gland dysfunction
PurposeTo assess the effects of 1% azithromycin ophthalmic solution (AZM) in patients with bacterial blepharitis accompanied by meibomian gland...
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Engineering for a clear image: a comparative focus on accommodation
The eye requires the ability to focus images near and far and throughout evolution numerous mechanisms have developed to allow this accommodation....
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Natural compounds-based nanomedicines for cancer treatment: Future directions and challenges
Several efforts have been extensively accomplished for the amelioration of the cancer treatments using different types of new drugs and less...
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Long term surgical results and safety profile of the novel CM T Flex scleral fixated intraocular lens
PurposeTo report the long term visual outcomes and complications with use of the novel CM-T Flex scleral fixated intraocular lens (CMT-SFIOL).
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Inter-zonal epithelial thickness differences for early keratoconus detection using optical coherence tomography
PurposeTo develop and test a parameter for early keratoconus screening by quantifying the localized epithelial thickness differences in keratoconic...
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Breathing difficulties in a nonagenarian: a self report
This is a self report. It is age related because I am 96 years old; about 5 years ago I was asymptomatic in this respect. I describe the difficulties...
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How Can General Managers Best Leverage Medical Affairs Now and in the Future?
General managers (GMs) play a crucial role as enterprise leaders of the country affiliate of multi-national pharmaceutical companies, balancing...
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Statistical Signal Detection Algorithm in Safety Data: A Proprietary Method Compared to Industry Standard Methods
IntroductionSeveral quantitative methods have been established, in pharmacovigilance, to detect signals of disproportionate reporting (SDRs) from...
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Changes in cataract and refractive surgery practice patterns among JSCRS members over the past 20 years
PurposeTo evaluate changes in cataract and refractive surgery practice patterns among members of the Japanese Society of Cataract and Refractive...
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Assessing large language models’ accuracy in providing patient support for choroidal melanoma
PurposeThis study aimed to evaluate the accuracy of information that patients can obtain from large language models (LLMs) when seeking answers to...
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Association of systemic and demographic risk factors with prevalence of retinopathy in US adults with prediabetes
Background/ObjectivesTo investigate the relative contribution of systemic risk factors to retinopathy in prediabetes using a nationally...
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Posterior corneal stability after small incision lenticule extraction with different optical zones
BackgroundTo assess the changes in the posterior corneal surface following small incision lenticule extraction (SMILE) with different optical zones.
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Peptides and Wound Healing: From Monomer to Combination
Peptides are a kind of compounds formed by α-amino acids linked together by peptide bonds, which are also intermediate products of protein...
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Thiamylal serum concentration for refractory convulsive status epilepticus while associated decreased concentrations of concomitant antiepileptics: a case report
BackgroundTreating refractory status epilepticus (RSE) remains a challenge. Thiamylal can be used as a second- or third-line treatment; however, its...
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Exploration of Abiraterone acetate loaded Nanostructured lipid carriers for bioavailability improvement and circumvention of fast-fed variability
Abiraterone acetate (ABA), a biopharmaceutical class IV drug suffers from solubility and permeability pitfalls resulting in limited oral...
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Real world treatment outcomes in polypoidal choroidal vasculopathy in a Caucasian population of British ethnicity
PurposeTo assess treatment response of Polypoidal choroidal vasculopathy (PCV) in a Caucasian population of British ethnicity with intravitreal...
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Active trachoma and associated factors in children aged 1 to 9 years living in Sasiga rural districts, East Wallaga Zone, Ethiopia, in 2022: a community- based cross-sectional study
BackgroundTrachoma, caused by the bacteria Chlamydia trachomatous, is a contagious eye condition that frequently affects children and quickly spreads...
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Retinal and choroidal thickness in fuchs uveitis syndrome: a contralateral eye study
BackgroundTo investigate the subfoveal retinal and choroidal thickness in patients with unilateral Fuchs Uveitis Syndrome (FUS).
Methods ...