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Article English Imaging / radiology Oncology

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  1. Interrelationship between thyroid hormones and reduced renal function, a review article

    Background

    Understanding the relationship of thyroid hormones with the development of chronic kidney disease (CKD) has important clinical implications...

    Sadaf Agahi, Atieh Amouzegar, ... Ladan Mehran in Thyroid Research
    Article Open access 15 July 2024

  2. SHR-A1811 (antibody-drug conjugate) in advanced HER2-mutant non-small cell lung cancer: a multicenter, open-label, phase 1/2 study

    A dose-escalation and expansion, phase 1/2 study (ClinicalTrials.gov, NCT04818333) was conducted to assess the novel antibody-drug conjugate...

    Ziming Li, Zhengbo Song, ... Shun Lu in Signal Transduction and Targeted Therapy
    Article Open access 15 July 2024

  3. Map** alternative splicing events in colorectal cancer

    Although aberrant splicing events of genes are closely related to the development and progression of colorectal cancer (CRC), the map** of abnormal...

    Yifeng Zheng, Guoqiang Zhong, ... Mingsong Li in Discover Oncology
    Article Open access 15 July 2024

  4. Comparison of the dosimetry of scandium-43 and scandium-44 patient organ doses in relation to commonly used gallium-68 for imaging neuroendocrine tumours

    Background

    Several research groups have explored the potential of scandium radionuclides for theragnostic applications due to their longer half-lives...

    Carlos Vinícius Gomes, Bruno Melo Mendes, ... Thiago Viana Miranda Lima in EJNMMI Physics
    Article Open access 15 July 2024

  5. Detection and characterization of autoreactive memory stem T-cells in children with acute immune thrombocytopenia

    Primary immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by an isolated decrease in platelets below 100 × 10 9 /l after...

    Asmaa M. Zahran, Omnia H. El-Badawy, ... Khalid I. Elsayh in Clinical and Experimental Medicine
    Article Open access 15 July 2024

  6. Efficacy and Safety of Salvage-line Nivolumab Monotherapy for Advanced Esophageal Squamous Cell Carcinoma: Comparison of 240 mg Versus 480 mg Doses

    Background

    Nivolumab monotherapy is the standard second-line treatment for advanced esophageal squamous cell carcinoma (ESCC) after failure of...

    Yuko Murashima, Shun Yamamoto, ... Ken Kato in Journal of Gastrointestinal Cancer
    Article Open access 15 July 2024

  7. Evaluating [225Ac]Ac-FAPI-46 for the treatment of soft-tissue sarcoma in mice

    Purpose

    Fibroblast Activation Protein (FAP) is an emerging theranostic target that is highly expressed on cancer-associated fibroblasts and on certain...

    Marco F. Taddio, Suraj Doshi, ... Christine E. Mona in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 15 July 2024

  9. TOTEM: a multi-cancer detection and localization approach using circulating tumor DNA methylation markers

    Background

    Detection of cancer and identification of tumor origin at an early stage improve the survival and prognosis of patients. Herein, we...

    Dalin **ong, Tiancheng Han, ... Chunguang Li in BMC Cancer
    Article Open access 15 July 2024

  10. SNCA is a potential therapeutic target for COVID-19 infection in diffuse large B-cell lymphoma patients

    Cuprotosis related genes (CRGs) have been proved to be potential therapeutic targets for coronavirus disease 2019 (COVID-19) and cancer, but their...

    Can Chen, Yun Li, ... Shenxian Qian in Apoptosis
    Article Open access 15 July 2024

  11. A simple projection method to correlate the principal mechanical direction with the principal microstructural direction of human osteoporotic femoral heads

    The mechanics of the trabecular bone is related to its structure; this work aimed to propose a simple projection method to clarify the correlation...

    Heming Chen, Dong Wang, ... Qiang Chen in Medical & Biological Engineering & Computing
    Article 15 July 2024

  13. ACTH-producing adrenocortical carcinoma: an exceedingly rare diagnosis

    Background

    Adrenocortical carcinoma is a very rare endocrinopathy that has a poor prognosis and is frequently associated with ACTH-independent...

    Miguel Saraiva, Raquel da Inez Correia, ... Isabel Palma in Journal of the Egyptian National Cancer Institute
    Article Open access 15 July 2024

  14. Sex ratio at birth across 100 years in Sweden and risk of cardiovascular disease and all-cause mortality – a national register study

    The human sex ratio at birth (SRB) undergoes temporary changes around a mean proportion of 0.51 male births. SRB has been well studied for...

    Peter M. Nilsson, Kristina Sundquist, ... **njun Li in European Journal of Epidemiology
    Article Open access 15 July 2024

  15. Unveiling the PDK4-centered rituximab-resistant mechanism in DLBCL: the potential of the “Smart” exosome nanoparticle therapy

    Background

    Diffuse large B-cell lymphoma (DLBCL) represents a prevalent malignant tumor, with approximately 40% of patients encountering treatment...

    **n Wu, Chunmei Ban, ... Qiangqiang Zhao in Molecular Cancer
    Article Open access 15 July 2024

  16. Impact on Glycemia Risk Index and other metrics in type 1 adult patients switching to Advanced Hybrid Closed-Loop systems: a one-year real-life experience

    Background

    Advanced Hybrid Closed-Loop system (AHCL) has profoundly changed type 1 diabetes therapy. This study primarily aimed to assess the impact...

    Eugenia Resmini, Emanuela Zarra, ... Angela Girelli in European Journal of Medical Research
    Article Open access 15 July 2024

  18. Zinc Supplementation Reduces ROS Production and Prevents MDMA-Induced Apoptosis in TM3 Leydig Cells via the Inhibition of Pro-Apoptotic Proteins

    MDMA can cause serious adverse effects on vital organs such as the heart, brain, and liver. Additionally, MDMA consumption can also potentially cause...

    Salar Mahmoudi-Nejad, Sina Ahmadi, ... Morteza Bagheri in Biological Trace Element Research
    Article 15 July 2024

  19. Measurement of left ventricular volume with admittance incorporated onto percutaneous ventricular assist device

    Percutaneous ventricular assist devices (pVADs) incorporated with admittance electrodes have been validated in animal studies for accurate...

    Luis A. Diaz Sanmartin, Aleksandra B. Gruslova, ... Jonathan W. Valvano in Medical & Biological Engineering & Computing
    Article 15 July 2024

  20. FDG altered biodistribution in white adipose tissue, a rare entity: case report and review of the literature

    Purpose

    Altered 18 F-fluorodeoxyglucose (FDG) biodistribution due to patient factors such as exercise and inadequate fasting are well established...

    William Y. Raynor, Stephen J. Sozio, Jeffrey S. Kempf in EJNMMI Reports
    Article Open access 15 July 2024
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