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Survival of advanced/recurrent gastrointestinal stromal tumors treated with tyrosine kinase inhibitors in Taiwan: a nationwide registry study
BackgroundMost gastrointestinal stromal tumors (GISTs) harbor c-KIT or PDGFRA mutations. Administration of tyrosine kinase inhibitors (TKIs) has...
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Machine learning to optimize literature screening in medical guideline development
ObjectivesIn a time of exponential growth of new evidence supporting clinical decision-making, combined with a labor-intensive process of selecting...
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Digital biomarkers for non-motor symptoms in Parkinson’s disease: the state of the art
Digital biomarkers that remotely monitor symptoms have the potential to revolutionize outcome assessments in future disease-modifying trials in...
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Survey on pattern of myopia in school children in Hangzhou after the COVID-19 pandemic: a school-based vision screening study
BackgroundMyopia is a major health issue around the world. Myopia in children has increased significantly during the COVID-19 pandemic in China, but...
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Eyecare-cloud: an innovative electronic medical record cloud platform for pediatric research and clinical care
Background and objectivesClinical data are essential for develo** cloud platforms for intelligent diagnosis and treatment decision of diseases....
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The association between air pollution and obesity: an umbrella review of meta-analyses and systematic reviews
The objective of this umbrella review was to investigate comprehensive and synthesized evidence of the association between ambient air pollution and...
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The relationship between follicle-stimulating hormone and metabolic dysfunction-associated fatty liver disease in men
ObjectivesThe present study aimed to investigate the relationship between male hormones and metabolic dysfunction-associated fatty liver disease...
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Breastfeeding support among healthcare workers in Nigeria
BackgroundThe exclusive breastfeeding rate in Sub-Saharan Africa is abysmally low, and based on current trends, achieving the World Health...
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From bench to bedside: the application of cannabidiol in glioma
Glioma is the most common malignant tumor in central nervous system, with significant health burdens to patients. Due to the intrinsic...
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Biliary atresia
Biliary atresia (BA) is a progressive inflammatory fibrosclerosing disease of the biliary system and a major cause of neonatal cholestasis. It...
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A two-pronged approach to understanding reciprocity and mental health relationship in develo** countries: evidence from young informal construction workers in Nigeria
BackgroundMental health problems disproportionately affect young people in develo** countries. However, there is limited research on help-seeking...
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The spectrum of health conditions in community-based cross-sectional surveys in Southeast Asia 2010-21: a sco** review
BackgroundSoutheast Asia is undergoing an epidemiological transition with non-communicable illnesses becoming increasingly important, yet infectious...
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Unravelling factors influencing demand for modern contraception and evaluating coverage progress since 2015 in Ethiopia, Kenya, and Nigeria: insights from multilevel and geostatistical modelling
IntroductionThe United Nations established the Sustainable Development Goals (SDGs) in 2015 to enhance global development. In this study, we examine...
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Identification of risk factors of Long COVID and predictive modeling in the RECOVER EHR cohorts
BackgroundSARS-CoV-2-infected patients may develop new conditions in the period after the acute infection. These conditions, the post-acute sequelae...
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Maternal distress, parenting stress, maladaptive parenting and children’s problematic media use in China: evidence from 2022 spring in Shanghai
The COVID-19 lockdown has forced young children to spend more time on media and significantly impacted their mothers’ mental health. This study...
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Insights from an N3C RECOVER EHR-based cohort study characterizing SARS-CoV-2 reinfections and Long COVID
BackgroundAlthough the COVID-19 pandemic has persisted for over 3 years, reinfections with SARS-CoV-2 are not well understood. We aim to characterize...
