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Mitochondrial DNA abundance in blood is associated with Alzheimer’s disease- and dementia-risk
The mitochondrial cascade hypothesis of Alzheimer’s disease (AD) has been portrayed through molecular, cellular, and animal studies; however large...
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Breast cancer preventive practices and associated factors among reproductive age women in Wadila District, North East Ethiopia: community based cross-sectional study
BackgroundCancer is one of the leading causes of morbidity and mortality worldwide. Among all cancer types, breast cancer stands out as the most...
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The abortion trend after the pronatalist turn of population policies in Iran: a systematic review from 2005 to 2022
ObjectiveGiven Iran’s recent shift towards pronatalist population policies, concerns have arisen regarding the potential increase in abortion rates....
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A multidisciplinary group-based survivorship intervention for those living with multiple myeloma: a feasibility study
BackgroundWhile multiple myeloma continues to be an incurable cancer, advances in its understanding and management have led to significantly improved...
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Using the illness-death model to estimate age- and sex-standardized incidence rates of diabetes in Mexico from 2003 to 2015
BackgroundWe aimed to estimate the age-specific and age-standardized incidence rate of diabetes for men and women in Mexico between 2003 and 2015,...
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The transition from tube feeding to oral feeding algorithm in preterm infants: case-control study
BackgroundOral feeding is a complex sensorimotor process influenced by many variables, making it challenging for healthcare providers to introduce...
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The effectiveness of the WHO school mental health package in promoting mental health literacy among secondary school teachers in Qatar: a randomized controlled trial
Teachers’ mental health literacy (MHL) is fundamental for recognizing and assisting students with mental disorders. The aim of this study was to...
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Assessing the suitability of video-assisted anal fistula treatment for obese patients compared to conventional surgery: a question worth investigating
Background and aimsVideo-assisted anal fistula treatment (VAAFT) is an innovative surgical approach enabling the direct visualization of the fistula...
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Risk factors associated with underweight in children aged one to two years: a longitudinal study
BackgroundUnderweight is a prevalent health issue in children. This study aimed to identify factors associated with underweight in children aged 1–2...
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SHR-A1811 (antibody-drug conjugate) in advanced HER2-mutant non-small cell lung cancer: a multicenter, open-label, phase 1/2 study
A dose-escalation and expansion, phase 1/2 study (ClinicalTrials.gov, NCT04818333) was conducted to assess the novel antibody-drug conjugate...
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Factors affecting decisions of an HMO Drug Exemptions Committee on individual patient requests for coverage of non-formulary drugs
BackgroundIn Israel, coverage of health needs is delivered by four health maintenance organizations (HMOs), which are budgeted by the government...
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Map** alternative splicing events in colorectal cancer
Although aberrant splicing events of genes are closely related to the development and progression of colorectal cancer (CRC), the map** of abnormal...
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Perception of couples’ on multipurpose prevention technology attribute choice: the case of MTN 045
BackgroundMultipurpose prevention technologies (MPTs) are products capable of simultaneously addressing multiple sexual and reproductive health needs...
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Lessons from the physiological role of guanosine in neurodegeneration and cancer: Toward a multimodal mechanism of action?
Neurodegenerative diseases and brain tumours represent important health challenges due to their severe nature and debilitating consequences that...
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Coronary periarteritis and pericarditis are rare but distinct manifestations of heart involvement in IgG4-related disease: a retrospective cohort study
BackgroundThe heart can be involved in immunoglobulin (Ig)-G4-related disease (IgG4-RD). This study aimed to summarize the clinical features and...
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Autoantibodies Neutralizing GM-CSF in HIV-Negative Colombian Patients Infected with Cryptococcus gattii and C. neoformans
BackgroundCryptococcosis is a life-threatening disease caused by Cryptococcus neoformans or C. gattii . Neutralizing autoantibodies (auto-Abs)...
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Effects of high-intensity interval training on cardiometabolic biomarkers in patients with prostate cancer undergoing active surveillance: a randomized controlled trial
PurposeTo report the effects of a 12-week high-intensity interval training (HIIT) program on cardiometabolic biomarkers in patients with prostate...