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  1. Early oxidative stress and DNA damage in Aβ-burdened hippocampal neurons in an Alzheimer’s-like transgenic rat model

    Oxidative stress is a key contributor to AD pathology. However, the earliest role of pre-plaque neuronal oxidative stress, remains elusive. Using...

    Morgan K. Foret, Chiara Orciani, ... Sonia Do Carmo in Communications Biology
    Article Open access 14 July 2024
  2. A versatile functional interaction between electrically silent KV subunits and KV7 potassium channels

    Voltage-gated K + (K V ) channels govern K + ion flux across cell membranes in response to changes in membrane potential. They are formed by the assembly...

    Vijay Renigunta, Nermina Xhaferri, ... Moritz Lindner in Cellular and Molecular Life Sciences
    Article Open access 14 July 2024
  3. Genomic characterization and virulence gene profiling of Erysipelothrix rhusiopathiae isolated from widespread muskox mortalities in the Canadian Arctic Archipelago

    Background

    Muskoxen are important ecosystem components and provide food, economic opportunities, and cultural well-being for Indigenous communities in...

    Lakshmi Vineesha Seru, Taya L. Forde, ... Susan J. Kutz in BMC Genomics
    Article Open access 14 July 2024
  4. Identification of volatile metabolites produced from levodopa metabolism by different bacteria strains of the gut microbiome

    Interspecies pathways in the gut microbiome have been shown to metabolize levodopa, the primary treatment for Parkinson’s disease, and reduce its...

    Taylor Pennington, Jarrett Eshima, Barbara S. Smith in BMC Microbiology
    Article Open access 13 July 2024
  5. The acyl-CoA-binding protein VdAcb1 is essential for carbon starvation response and contributes to virulence in Verticillium dahliae

    In the face of carbon, nitrogen, and phosphorus starvation, microorganisms have evolved adaptive mechanisms to maintain growth. In a previous study,...

    **g Zhuang, Ya-Duo Zhang, ... Dan-Dan Zhang in aBIOTECH
    Article Open access 13 July 2024
  6. CRISPR screens in 3D tumourspheres identified miR-4787-3p as a transcriptional start site miRNA essential for breast tumour-initiating cell growth

    Our study employs pooled CRISPR screens, integrating 2D and 3D culture models, to identify miRNAs critical in Breast Cancer (BC) tumoursphere...

    Tom Stiff, Salih Bayraktar, ... Leandro Castellano in Communications Biology
    Article Open access 13 July 2024
  7. Unveiling the Role of Angiosperm Pollen Morphology in Attachment to the Moth (Lepidoptera) Proboscides

    Abstract

    The current study aims to understand the role of various morphological features of pollen grains in attachment with moth proboscides. To test...

    Dipayan Mitra, Rajesh Lenka, ... Navneet Singh in Biology Bulletin
    Article 13 July 2024
  8. Sexual Size Dimorphism in Buthus tunetanus (Scorpiones: Buthidae) from Tunisia

    Abstract

    Scorpions are known to exhibit sexual size dimorphism, but data is still lacking from a large number of species throughout the world. Such...

    Sarra Hajri, Jamel Babay, ... Saïd Nouira in Biology Bulletin
    Article 13 July 2024
  9. Evaluation of heritability partitioning approaches in livestock populations

    Background

    Heritability partitioning approaches estimate the contribution of different functional classes, such as coding or regulatory variants, to...

    Can Yuan, José Luis Gualdrón Duarte, ... Tom Druet in BMC Genomics
    Article Open access 13 July 2024
  10. Identification of Tissue Expression Characteristics of Pig ALKBH5 and Its Association with Pathogenic Microbial Infection

    Abstract

    N 6 -methyladenosine (m 6 A) as a reversible RNA modification has become a new direction and hotspot of RNA epigenetics research in the field of...

    Yuan Bian, Yifan Xu, ... Zhengchang Wu in Biology Bulletin
    Article 13 July 2024
  11. Preclinical and clinical advances to overcome hypoxia in glioblastoma multiforme

    Glioblastoma multiforme (GBM) is the most common adult primary brain tumor. The standard clinical treatment of GBM includes a maximal surgical...

    Jolie Bou-Gharios, Georges Noël, Hélène Burckel in Cell Death & Disease
    Article Open access 13 July 2024
  12. Growth Characteristics of 10 Deep-Sea Demersal Scorpaenoid Fish Species from the Arabian Sea: Insights for Database Update and Fisheries Management

    Abstract

    The present study provides length-weight relationships (LWRs) and condition factors (Kn) estimates for ten deep-sea scorpaeniform fishes...

    D. Nihal, K. V. Aneesh Kumar, ... H. Manjebrayakath in Biology Bulletin
    Article 13 July 2024
  13. DNA Barcoding of Tree Frogs: Testing the Existence of Two Mitochondrial Lineages of Hyla savignyi

    Abstract

    DNA barcoding is a popular approach that can aid in identifying species and has led to the discovery of many new amphibian species. In this...

    T. Ergül Kalaycı in Biology Bulletin
    Article 13 July 2024
  14. Psychological and ethical issues raised by genomic in paediatric care pathway, a qualitative analysis with parents and childhood cancer patients

    In paediatric oncology, genomics raises new ethical, legal and psychological issues, as somatic and constitutional situations intersect throughout...

    Marion Droin-Mollard, Sandrine de Montgolfier, ... Khadija Lahlou-Laforêt in European Journal of Human Genetics
    Article Open access 13 July 2024
  15. C4-like Sesuvium sesuvioides (Aizoaceae) exhibits CAM in cotyledons and putative C4-like + CAM metabolism in adult leaves as revealed by transcriptome analysis

    Background

    The co-occurrence of C 4 and CAM photosynthesis in a single species seems to be unusual and rare. This is likely due to the difficulty in...

    Christian Siadjeu, Gudrun Kadereit in BMC Genomics
    Article Open access 13 July 2024
  16. Age-related dysregulation of CXCL9/10 in monocytes is linked to impaired innate immune responses in a mouse model of Staphylococcus aureus osteomyelitis

    Background

    Age-associated impairments in innate immunity are believed to be a causative factor responsible for severe pathogenesis of Staphylococcus...

    Yihuang Lin, Mankai Yang, ... **anrong Zhang in Cellular and Molecular Life Sciences
    Article Open access 13 July 2024
  17. Evaluation of the Irrigation Water Quality of Beressa River, North West Ethiopia

    Beressa River is facing a problem due to uncontrolled discharge of liquid wastes from domestics and industries. Therefore, the study was conducted to...

    Article 13 July 2024
  18. Modelling Role of Protective and Nonprotective HLA Allele Inducing Different HIV Infection Outcomes

    Human immunodeficiency virus (HIV) infects CD4+ cells and causes progressive immune function failure, and CD8+ cells lyse infected CD4+ cell via...

    Article Open access 13 July 2024
  19. A novel deep-benthic sea cucumber species of Benthodytes (Holothuroidea, Elasipodida, Psychropotidae) and its comprehensive mitochondrial genome sequencing and evolutionary analysis

    Background

    The holothurians, commonly known as sea cucumbers, are marine organisms that possess significant dietary, nutritional, and medicinal value....

    Yingying He, Hancheng Zhao, ... **lai Miao in BMC Genomics
    Article Open access 13 July 2024
  20. Phylogenetic Inference from 16S rRNA Gene Sequencing in Chromosome Races of the Genus Nannospalax Species (Rodentia: Spalacidae)

    Abstract

    In this study, we aimed to develop a species-level phylogeny for the Nannospalax genus, identify cryptic species that are difficult to...

    Teoman Kankılıç, Habibe Didem Çelikbilek, ... İlkay Civelek in Biology Bulletin
    Article 13 July 2024
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